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Yusuf Hamied Department of Chemistry

 

Publications by Professor Andreas Bender

Novel Synthetic Biscoumarins Target Tumor Necrosis Factor-α in Hepatocellular Carcinoma <i>in Vitro</i> and <i>in Vivo</i>
HK Keerthy, CD Mohan, KS Siveen, JE Fuchs, S Rangappa, MS Sundaram, F Li, KS Girish, G Sethi, Basappa, A Bender, KS Rangappa
– The Journal of biological chemistry
(2014)
289,
31879
(DOI: 10.1074/jbc.m114.593855)
Toxicity prediction using heterogeneous chemical and biological data sources
A Bender
– Toxicology Letters
(2014)
229,
S4
(DOI: 10.1016/j.toxlet.2014.06.040)
Predicting Toxic Effects of Metabolites
A Bender
(2014)
397
(DOI: 10.1002/9783527673261.ch16)
Novel Benzoxazine-Based Aglycones Block Glucose Uptake <i>In Vivo</i> by Inhibiting Glycosidases
H Bharathkumar, MS Sundaram, S Jagadish, S Paricharak, M Hemshekhar, D Mason, K Kemparaju, KS Girish, Basappa, A Bender, KS Rangappa
– Plos One
(2014)
9,
e102759
(DOI: 10.1371/journal.pone.0102759)
Proteochemometric modeling in a Bayesian framework.
I Cortes-Ciriano, GJ van Westen, EB Lenselink, DS Murrell, A Bender, T Malliavin
– J Cheminform
(2014)
6,
35
(DOI: 10.1186/1758-2946-6-35)
A community effort to assess and improve drug sensitivity prediction algorithms
JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, M Bansal, M Ammad-ud-din, P Hintsanen, SA Khan, J-P Mpindi, O Kallioniemi, A Honkela, T Aittokallio, K Wennerberg, NCI DREAM Community, JJ Collins, D Gallahan, D Singer, J Saez-Rodriguez, S Kaski, JW Gray, G Stolovitzky
– Nature Biotechnology
(2014)
32,
1202
(DOI: 10.1038/nbt.2877)
Towards predictive resistance models for agrochemicals by combining chemical and protein similarity via proteochemometric modelling
GJP van Westen, A Bender, JP Overington
– BMC Chemistry
(2014)
7,
119
(DOI: 10.1007/s12154-014-0112-2)
Biofragments: an approach towards predicting protein function using biologically related fragments and its application to Mycobacterium tuberculosis CYP126.
SA Hudson, EH Mashalidis, A Bender, KJ McLean, AW Munro, C Abell
– Chembiochem : a European journal of chemical biology
(2014)
15,
549
(DOI: 10.1002/cbic.201300697)
Modelling ligand selectivity of serine proteases using integrative proteochemometric approaches improves model performance and allows the multi-target dependent interpretation of features.
QU Ain, O Méndez-Lucio, IC Ciriano, T Malliavin, GJP van Westen, A Bender
– Integrative biology : quantitative biosciences from nano to macro
(2014)
6,
1023
(DOI: 10.1039/c4ib00175c)
Synthesis and biological evaluation of tetrahydropyridinepyrazoles ('PFPs') as inhibitors of STAT3 phosphorylation
CN Revanna, V Srinivasa, F Li, KS Siveen, X Dai, SN Swamy, DG Bhadregowda, G Sethi, K Mantelingu, A Bender, R Ks
– MedChemComm
(2014)
5,
32
(DOI: 10.1039/c3md00119a)
Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ
H Bharathkumar, S Paricharak, KR Dinesh, KS Siveen, JE Fuchs, S Rangappa, CD Mohan, N Mohandas, AP Kumar, G Sethi, A Bender, Basappa, KS Rangappa
– RSC Adv.
(2014)
4,
45143
(DOI: 10.1039/c4ra08713e)
Comparative mode-of-action analysis following manual and automated phenotype detection in Xenopus laevis
G Drakakis, AE Hendry, K Hanson, SC Brewerton, MJ Bodkin, DA Evans, GN Wheeler, A Bender
– RSC Medicinal Chemistry
(2014)
5,
386
(DOI: 10.1039/c3md00313b)
Are phylogenetic trees suitable for chemogenomics analyses of bioactivity data sets: the importance of shared active compounds and choosing a suitable data embedding method, as exemplified on Kinases.
S Paricharak, T Klenka, M Augustin, UA Patel, A Bender
– Journal of Cheminformatics
(2013)
5,
49
(DOI: 10.1186/1758-2946-5-49)
How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space
A Koutsoukas, S Paricharak, WRJD Galloway, DR Spring, AP Ijzerman, RC Glen, D Marcus, A Bender
– Journal of chemical information and modeling
(2013)
54,
230
(DOI: 10.1021/ci400469u)
Design, synthesis and biological evaluation of a novel allosteric inhibitor of HSET that damages cancer cells with supernumerary centrosomes.
CA Watts, FM Richards, A Bender, PJ Bond, O Korb, O Kern, M Riddick, P Owen, RM Myers, J Raff, F Gergely, DI Jodrell, SV Ley
– Molecular Cancer Therapeutics
(2013)
12,
B96
(DOI: 10.1158/1535-7163.TARG-13-B96)
Design, Synthesis, and Biological Evaluation of an Allosteric Inhibitor of HSET that Targets Cancer Cells with Supernumerary Centrosomes
CA Watts, FM Richards, A Bender, PJ Bond, O Korb, O Kern, M Riddick, P Owen, RM Myers, J Raff, F Gergely, DI Jodrell, SV Ley
– Cell Chemical Biology
(2013)
20,
1399
(DOI: 10.1016/j.chembiol.2013.09.012)
Experimental Confirmation of New Drug-Target Interactions Predicted by Drug Profile Matching
L Végner, Á Peragovics, L Tombor, B Jelinek, P Czobor, A Bender, Z Simon, A Málnási-Csizmadia
– J Med Chem
(2013)
56,
8377
(DOI: 10.1021/jm400813y)
Extensions to In Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts.
S Liggi, G Drakakis, AE Hendry, KM Hanson, SC Brewerton, GN Wheeler, MJ Bodkin, DA Evans, A Bender
– Molecular Informatics
(2013)
32,
1009
(DOI: 10.1002/minf.201300102)
Benchmarking of protein descriptor sets in proteochemometric modeling (part 1): Comparative study of 13 amino acid descriptor sets
GJ van Westen, RF Swier, I Cortes-Ciriano, JK Wegner, JP Overington, AP Ijzerman, HW van Vlijmen, A Bender
– J Cheminform
(2013)
5,
42
(DOI: 10.1186/1758-2946-5-42)
Benchmarking of protein descriptor sets in proteochemometric modeling (part 1): comparative study of 13 amino acid descriptor sets.
GJ van Westen, RF Swier, JK Wegner, AP Ijzerman, HW van Vlijmen, A Bender
– J Cheminform
(2013)
5,
41
(DOI: 10.1186/1758-2946-5-41)

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