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Yusuf Hamied Department of Chemistry


We are interested in molecular recognition, aiming to uncover and exploit the rules governing non-covalent interactions. Hydrophobic, π–π, donor–acceptor, metal– ligand and hydrogen bonding interactions are used to create new supramolecular systems that expand our understanding of molecular behaviour and may have useful recognition, catalytic or photophysical properties. In particular in the past few years we have developed the concept of dynamic combinatorial chemistry as a new approach for discovering entirely unexpected structures and assemblies. Over the years our building blocks have included peptides, metalloporphyrins, steroids and simple aromatics, and our products have included macrocycles, rotaxanes, catenanes, molecular knots and supramolecular nanotubes. Very recently, while investigating dynamic chemistry in the solid state using ball mill grinding, we have discovered solvent and surface effects on polymorph stability in nanocrystals

Please note that I am not taking any new students or postdocs into my research group.




Selected Publications


Evolution of dynamic combinatorial chemistry, Accounts Chem. Res., (2012), 45, 2211.

Discovery of an organic trefoil knot, Science, (2012), 338, 783.

Templated dynamic synthesis of a [3]Catenane, Angew. Chemie Intl. Edn., (2012), 51, 1443.

Thermodynamics of supramolecular naphthalenediimide nanotubes, J. Am. Chem. Soc., (2012), 134, 566.

Discovery of linear receptors for multiple dihydrogen phosphate ions using dynamic combinatorial chemistry, J. Am. Chem. Soc., (2011), 133, 3804.

Formation pathways of Donor-Acceptor catenanes in aqueous dynamic combinatorial libraries, J. Am. Chem. Soc., (2011), 133, 3198.

Solid-state dynamic combinatorial chemistry, Chem. Sci., (2011), 2, 696.

An unexpected receptor for C70, Angew. Chemie Intl. Edn., (2008), 47, 2689.


Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments.
AM Belenguer, GI Lampronti, JKM Sanders
– J Vis Exp
ARTN e56824
(DOI: 10.3791/56824)
Onwards and upwards: towards a sustainable future
JKM Sanders
– Royal Society open science
JKM Sanders
– Royal Society Open Science
Reviewers in 2016
JKM Sanders
– R Soc Open Sci
Selective C-70 encapsulation by a robust octameric nanospheroid held together by 48 cooperative hydrogen bonds
G Markiewicz, A Jenczak, M Kołodziejski, JJ Holstein, JKM Sanders, AR Stefankiewicz
– Nat Commun
Dudley Howard Williams. 25 May 1937 — 3 November 2010
JKM Sanders, DCV Robinson
– Biographical Memoirs of Fellows of the Royal Society
Transparency and openness in science.
J Sanders, J Blundy, A Donaldson, S Brown, R Ivison, M Padgett, K Padian, K Rittinger, K Rowe, A Stace, E Viding, C Chambers, M Chaplain
– R Soc Open Sci
Solvation and surface effects on polymorph stabilities at the nanoscale.
AM Belenguer, GI Lampronti, AJ Cruz-Cabeza, CA Hunter, JKM Sanders
– Chemical Science
Cambridge’s global mission: A primary school at the heart.
JKM Sanders, J Nicholls, J Rose
From lanthanide shift reagents to molecular knots: the importance of molecular and mental flexibility.
JKM Sanders
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Research Group

Research Interest Groups

Telephone number

01223 336411

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