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Georg Meisl

 


Sidney Sussex College Research Fellow


 


Education


​2016 - PhD in Biophysical Chemistry, University of Cambridge


2011 - MSci in Natural Sciences, Chemistry, UNiversity of Cambridge


2010 - Cambridge-MIT Exchange Program, Massachusetts Institute of Technology


 


Research Interests


Development and application of fundamental biophysical theories to data analysis in a biologically relevant context, Protein Aggregation, Biophysical Chemistry, High Throughput Screening


 


Selected Publications


 

Publications

Secondary nucleation in amyloid formation.
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, SIA Cohen, TPJ Knowles, S Linse
– Chemical communications (Cambridge, England)
(2018)
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils.
JWP Brown, G Meisl, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
– Chemical communications (Cambridge, England)
(2018)
54,
7854
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, GT Heller, G Meisl, SW Chen, JR Kumita, PK Challa, JB Kirkegaard, SIA Cohen, B Mannini, D Barbut, EAA Nollen, C Cecchi, N Cremades, TPJ Knowles, F Chiti, M Zasloff, M Vendruscolo, CM Dobson
– ACS Chem Biol
(2018)
Oligomer diversity during the aggregation of the repeat-region of tau
M Kjaergaard, AJ Dear, F Kundel, S Qamar, G Meisl, TPJ Knowles, D Klenerman
– ACS Chemical Neuroscience
(2018)
On the role of sidechain size and charge in the aggregation of A beta 42 with familial mutations
X Yang, G Meisl, B Frohm, E Thulin, TPJ Knowles, S Linse
– Proceedings of the National Academy of Sciences of the United States of America
(2018)
115,
E5849
Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, N Esteras, AY Abramov, TJP Knowles, M Goedert, D Klenerman
– ACS Chemical Neuroscience
(2018)
9,
1276
On-chip measurements of protein unfolding from direct observations of micron-scale diffusion.
Y Zhang, EV Yates, L Hong, KL Saar, G Meisl, CM Dobson, TPJ Knowles
– Chemical Science
(2018)
9,
3503
Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein-Lipid Interactions.
H Gang, C Galvagnion, G Meisl, T Müller, M Pfammatter, AK Buell, A Levin, CM Dobson, B Mu, TPJ Knowles
– Anal Chem
(2018)
90,
3284
Kinetic Analysis of Amyloid Formation.
G Meisl, TCT Michaels, S Linse, TPJ Knowles
– Methods Mol Biol
(2018)
1779,
181
Absolute Quantification of Amyloid Propagons by Digital Microfluidics
M Pfammatter, M Andreasen, G Meisl, CG Taylor, J Adamcik, S Bolisetty, A Sánchez-Ferrer, D Klenerman, CM Dobson, R Mezzenga, TPJ Knowles, A Aguzzi, S Hornemann
– Anal Chem
(2017)
89,
12306
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Research Group

Telephone number

01223 763845 (shared)

Email address

gm373@cam.ac.uk