skip to content

Yusuf Hamied Department of Chemistry

 

Research Associate

 

Education

​2016 - PhD in Biophysical Chemistry, University of Cambridge

2011 - MSci in Natural Sciences, Chemistry, UNiversity of Cambridge

2010 - Cambridge-MIT Exchange Program, Massachusetts Institute of Technology

 

Research Interests

Development and application of fundamental biophysical theories to data analysis in a biologically relevant context, Protein Aggregation, Biophysical Chemistry, High Throughput Screening

 

Selected Publications

 

Publications

Molecular mechanism of α-synuclein aggregation on lipid membranes revealed
AJ Dear, X Teng, SR Ball, J Lewin, RI Horne, D Clow, N Harper, K Yahya, TCT Michaels, S Linse, TPJ Knowles, X Yang, SC Brewerton, J Thomson, J Habchi, G Meisl
(2023)
Phase Separation and Fibrillization of Human Annexin A7 Are Mediated by Its Proline-Rich Domain.
C Yu, SL Nelson, G Meisl, R Ghirlando, L Deshmukh
– Biochemistry
(2023)
62,
3036
Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α-Synuclein at Physiological pH with Sodium Salts.
RI Horne, MA Metrick, W Man, DJ Rinauro, ZF Brotzakis, S Chia, G Meisl, M Vendruscolo
– ACS Chem Neurosci
(2023)
14,
3125
Self-replication of Aβ42aggregates occurs on small and isolated fibril sites
S Curk, J Krausser, G Meisl, D Frenkel, S Linse, T Michaels, T Knowles, A Šarić
(2023)
α-Synuclein oligomers form by secondary nucleation
C Xu, G Meisl, E Andrzejewska, G Krainer, A Dear, MC Cruz, S Turi, R Jacquat, W Arter, M Vendruscolo, S Linse, TPJ Knowles
(2023)
Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum
MM Schneider, T Scheidt, AJ Priddey, CK Xu, M Hu, G Meisl, SRA Devenish, CM Dobson, V Kosmoliaptsis, TPJ Knowles
– Biosensors & bioelectronics
(2023)
228,
115196
Perphenazine-Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid.
SR Ball, JSP Adamson, MA Sullivan, MR Zimmermann, V Lo, M Sanz-Hernandez, X Jiang, AH Kwan, ADJ McKenzie, EL Werry, TPJ Knowles, M Kassiou, G Meisl, MH Todd, PJ Rutledge, M Sunde
– ACS Chemical Neuroscience
(2022)
14,
87
Uncovering the universality of self-replication in protein aggregation and its link to disease
G Meisl, CK Xu, JD Taylor, TCT Michaels, A Levin, D Otzen, D Klenerman, S Matthews, S Linse, M Andreasen, TPJ Knowles
– Science advances
(2022)
8,
eabn6831
A conformational switch controlling the toxicity of the prion protein.
K Frontzek, M Bardelli, A Senatore, A Henzi, RR Reimann, S Bedir, M Marino, R Hussain, S Jurt, G Meisl, M Pedotti, F Mazzola, G Siligardi, O Zerbe, M Losa, T Knowles, A Lakkaraju, C Zhu, P Schwarz, S Hornemann, MG Holt, L Simonelli, L Varani, A Aguzzi
– Nat Struct Mol Biol
(2022)
29,
831
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
M Emmenegger, S Fiedler, SD Brugger, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, AY Malik, T Scheier, L Batkitar, L Madrigal, M Rossi, G Meisl, AK Lynn, L Saleh, A von Eckardstein, TPJ Knowles, A Aguzzi
– iScience
(2022)
25,
104766
  • 1 of 12
  • >

Research Group

Telephone number

01223 763845 (shared)
01223 763842

Email address

gm373@cam.ac.uk