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Yusuf Hamied Department of Chemistry

 

Publications by Professor Steven Lee

Capturing resting T cells: the perils of PLL.
AM Santos, A Ponjavic, M Fritzsche, RA Fernandes, JB de la Serna, MJ Wilcock, F Schneider, I Urbančič, J McColl, C Anzilotti, KA Ganzinger, M Aßmann, D Depoil, RJ Cornall, ML Dustin, D Klenerman, SJ Davis, C Eggeling, SF Lee
– Nature Immunology
(2018)
19,
203
(DOI: 10.1038/s41590-018-0048-8)
Maximizing the field of view and accuracy in 3D Single Molecule Localization Microscopy.
SA Rehman, AR Carr, MO Lenz, SF Lee, K O'Holleran
– Opt Express
(2018)
26,
4631
(DOI: 10.1364/oe.26.004631)
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Ghandi, SE Bohndiek, TN Snaddon, SF Lee
– R Soc Open Sci
(2018)
5,
171399
(DOI: 10.1098/rsos.171399)
Optical Structural Analysis of Individual α-Synuclein Oligomers.
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
– Angewandte Chemie International Edition
(2018)
57,
4886
(DOI: 10.1002/anie.201710779)
Single-Molecule Imaging of Wnt3A Protein Diffusion on Living Cell Membranes.
SF Lee, ND Evans, A Lippert, A Janeczek, A Fürstenberg, A Ponjavic, WE Moerner, R Nusse, J Helms
– Biophysical Journal
(2017)
113,
2762
(DOI: 10.1016/j.bpj.2017.08.060)
Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature.
F Daste, A walrant, MR Holst, JR Gadsby, J Mason, J Lee, D Brook, S Lee, M Mettlen, E Larsson, R Lundmark, JL Gallop
– J Cell Biol
(2017)
216,
3745
(DOI: 10.1083/jcb.201704061)
Receptor Quaternary Organization Explains G Protein-Coupled Receptor Family Structure
JH Felce, SL Latty, RG Knox, SR Mattick, Y Lui, SF Lee, D Klenerman, SJ Davis
– Cell Reports
(2017)
20,
2654
(DOI: 10.1016/j.celrep.2017.08.072)
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species
D Klenerman, M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, FS Ruggeri, T Guilliams, AK Buell, J-E Lee, S Gandhi, SF Lee, CE Bryant, M Vendruscolo, TPJ Knowles, CM Dobson, E De Genst, D Klenerman
– BMC Biol
(2017)
15,
57
(DOI: 10.1186/s12915-017-0390-6)
Ultrasensitive Measurement of Ca
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
– Angewandte Chemie (International ed. in English)
(2017)
56,
7750
(DOI: 10.1002/anie.201700966)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
– Angewandte Chemie
(2017)
129,
7858
(DOI: 10.1002/ange.201700966)
Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function.
AR Carr, A Ponjavic, S Basu, J McColl, AM Santos, S Davis, ED Laue, D Klenerman, SF Lee
– Biophys J
(2017)
112,
1444
(DOI: 10.1016/j.bpj.2017.02.023)
PEGylated Liposomes Associate With Wnt3A Protein and Expand Putative Stem Cells in Human Bone Marrow Populations
AA Janeczek, E Scarpa, MH Horrocks, RS Tare, CA Rowland, D Jenner, TA Newman, RO Oreffo, SF Lee, ND Evans
– Nanomedicine
(2017)
12,
845
(DOI: 10.2217/nnm-2016-0386)
3D structures of individual mammalian genomes studied by single-cell Hi-C
TJ Stevens, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee, M Leeb, KJ Wohlfahrt, W Boucher, A O’Shaughnessy-Kirwan, J Cramard, AJ Faure, M Ralser, E Blanco, L Morey, M Sanso, MGS Palayret, B Lehner, L Di Croce, A Wutz, B Hendrich, D Klenerman, ED Laue
– Nature
(2017)
544,
59
(DOI: 10.1038/nature21429)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
– Nature communications
(2016)
7,
13544
(DOI: 10.1038/ncomms13544)
A randomized control trial evaluating fluorescent ink $\textit{versus}$ dark ink tattoos for breast radiotherapy
SJ Landeg, AM Kirby, SF Lee, F Bartlett, K Titmarsh, E Donovan, CL Griffin, L Gothard, I Locke, HA McNair
– Br J Radiol
(2016)
89,
20160288
(DOI: 10.1259/bjr.20160288)
Nanoscopic Cellular Imaging: Confinement Broadens Understanding.
SA Lee, A Ponjavic, C Siv, SF Lee, JS Biteen
– ACS Nano
(2016)
10,
8143
(DOI: 10.1021/acsnano.6b02863)
A microfluidic platform for trapping, releasing and super-resolution imaging of single cells.
Y Zhou, S Basu, KJ Wohlfahrt, SF Lee, D Klenerman, ED Laue, AA Seshia
– Sensors and Actuators B Chemical
(2016)
232,
680
(DOI: 10.1016/j.snb.2016.03.131)
The Nucleosome Remodeling and Deacetylase Complex NuRD is built from preformed catalytically active sub-modules
W Zhang, A Aubert, JM Gomez de Segura, M Karuppasamy, S Basu, A Murthy, A Diamante, TA Drury, J Balmer, J Cramard, AA Watson, D Lando, SF Lee, M Palayret, S Kloet, A Smits, M Deery, M Vermeulen, B Hendrich, D Klenerman, C Schaffitzel, I Berger, ED Laue
– J Mol Biol
(2016)
428,
2931
(DOI: 10.1016/j.jmb.2016.04.025)
Studying the Dynamics of Chromatin-Binding Proteins in Mammalian Cells Using Single-Molecule Localisation Microscopy
S Basu, YL Tan, EJR Taylor, ED Laue, SF Lee
– Methods in molecular biology (Clifton, N.J.)
(2016)
1431,
235
(DOI: 10.1007/978-1-4939-3631-1_17)
PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits.
MJ Broadhead, MH Horrocks, F Zhu, L Muresan, R Benavides-Piccione, J DeFelipe, D Fricker, MV Kopanitsa, RR Duncan, D Klenerman, NH Komiyama, SF Lee, SGN Grant
– Sci Rep
(2016)
6,
24626
(DOI: 10.1038/srep24626)

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