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Yusuf Hamied Department of Chemistry

 
Conquering peaks and illuminating depths: developing stereocontrolled organic reactions to unlock nature's macrolide treasure trove
NYS Lam, TP Stockdale, MJ Anketell, I Paterson
– Chemical communications (Cambridge, England)
(2021)
57,
3171
The stereocontrolled total synthesis of polyketide natural products: a thirty-year journey
TP Stockdale, NYS Lam, MJ Anketell, I Paterson
– Bulletin of the Chemical Society of Japan
(2020)
94,
713
Total synthesis of the actinoallolides and a designed photoaffinity probe for target identification.
MJ Anketell, TM Sharrock, I Paterson
– Organic & Biomolecular Chemistry
(2020)
18,
8109
Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A
IE Ndukwe, X Wang, NYS Lam, K Ermanis, KL Alexander, MJ Bertin, GE Martin, G Muir, I Paterson, R Britton, JM Goodman, EJN Helfrich, J Piel, WH Gerwick, RT Williamson
– Chemical communications (Cambridge, England)
(2020)
56,
7565
Stereocontrolled Synthesis as an Enabling Tool for the Configurational Assignment of Marine Polyketide Natural Products
NYS Lam, I Paterson
– European Journal of Organic Chemistry
(2020)
2020,
2310
Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents
TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, JS Parker, DR Spring, I Paterson
– Chemical communications (Cambridge, England)
(2020)
56,
1529
A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti‐Trypanosomal Macrolides
MJ Anketell, TM Sharrock, I Paterson
– Angewandte Chemie
(2020)
132,
1588
Towards the Total Synthesis of Hemicalide: Synthesis of the C27-C46 Region
TP Stockdale, BY Han, NYS Lam, JM Goodman, I Paterson
– MARINE DRUGS
(2020)
18,
A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti‐Trypanosomal Macrolides
MJ Anketell, TM Sharrock, I Paterson
– Angewandte Chemie (International ed. in English)
(2019)
59,
1572
A counterintuitive stereochemical outcome from a chelation-controlled vinylmetal aldehyde addition leads to the configurational reassignment of phormidolide A.
NYS Lam, G Muir, VR Challa, R Britton, I Paterson
– Chemical communications (Cambridge, England)
(2019)
55,
9717
Synthesis-enabled stereochemical assignment of the C1-C28 region of hemicalide: A potent cytotoxic polyketide of marine sponge origin
N Lam, BY Han, C MacGregor, J Goodman, I Paterson
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
257,
Designed analogues of the aplyronines for next-generation antibody-drug conjugates
R Porter, T Pettigrew, I Paterson, D Spring, J Parker
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
257,
Toward the total synthesis of patellazole B: synthesis of an advanced C1–C25 fragment corresponding to the macrocyclic skeleton
AW Phillips, MJ Anketell, T Balan, NYS Lam, S Williams, I Paterson
– Org Biomol Chem
(2018)
16,
8286
A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine-site of tubulin
G Menchon, AE Prota, D Lucena-Agell, P Bucher, R Jansen, H Irschik, R Müller, I Paterson, JF Díaz, K-H Altmann, MO Steinmetz
– Nature Communications
(2018)
9,
2106
A synthesis-enabled relative stereochemical assignment of the c1-C28 region of hemicalide
BY Han, NYS Lam, CI MacGregor, JM Goodman, I Paterson
– Chemical communications (Cambridge, England)
(2018)
54,
3247
Toward Aplyronine Payloads for Antibody-Drug Conjugates: Total Synthesis of Aplyronines A and D
N AnŽiček, S Williams, MP Housden, I Paterson
– Organic & Biomolecular Chemistry
(2018)
16,
1343
Challenges and discoveries in the total synthesis of complex polyketide natural products
I Paterson, NYS Lam
– The Journal of antibiotics
(2017)
71,
215
Induction of accelerated senescence by the microtubule-stabilizing agent peloruside A.
A Chan, C Gilfillan, N Templeton, I Paterson, PT Northcote, JH Miller
– Investigational New Drugs
(2017)
35,
706
Structural Basis of Microtubule Stabilization by Discodermolide
AE Prota, K Bargsten, M Redondo-Horcajo, AB Smith, C-PH Yang, HM McDaid, I Paterson, SB Horwitz, J Fernando Díaz, MO Steinmetz
– Chembiochem
(2017)
18,
905
Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration
JJ Field, PT Northcote, I Paterson, K-H Altmann, JF Díaz, JH Miller
– International Journal of Molecular Sciences
(2017)
18,
971