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Yusuf Hamied Department of Chemistry

 
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes
– Nature Communications
(2016)
7,
13128
Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles
SB Carvalho, JM Freire, MG Moleirinho, F Monteiro, D Gaspar, MARB Castanho, MJT Carrondo, PM Alves, GJL Bernardes, C Peixoto
– Bioconjug Chem
(2016)
27,
2386
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, W-L Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, M-L Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
– Science
(2016)
354,
aag1465
Unveiling (−)‐Englerin A as a Modulator of L‐Type Calcium Channels
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
– Angewandte Chemie
(2016)
128,
11243
Tn Antigen Mimics Based on sp2-Iminosugars with Affinity for an anti-MUC1 Antibody
EMS Fernández, CD Navo, N Martínez-Sáez, R Gonçalves-Pereira, VJ Somovilla, A Avenoza, JH Busto, GJL Bernardes, G Jiménez-Osés, F Corzana, JMG Fernández, CO Mellet, JM Peregrina
– Organic Letters
(2016)
18,
3890
Correction: Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation
H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois
– Chem Sci
(2016)
7,
6280
Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
– Angewandte Chemie (International ed. in English)
(2016)
55,
11077
Iminoboronates are efficient intermediates for selective, rapid and reversible <i>N</i>-terminal cysteine functionalisation.
H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois
– Chem Sci
(2016)
7,
5052
Construction of homogeneous antibody-drug conjugates using site-selective protein chemistry.
P Akkapeddi, S-A Azizi, AM Freedy, PMSD Cal, PMP Gois, GJL Bernardes
– Chemical Science
(2016)
7,
2954
Urban Endocrine Disruptors Targeting Breast Cancer Proteins.
D Montes-Grajales, GJL Bernardes, J Olivero-Verbel
– Chemical Research in Toxicology
(2016)
29,
150
Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice
E Nogueira, F Lager, D Le Roux, P Nogueira, J Freitas, C Charvet, G Renault, A Loureiro, CR Almeida, A Ohradanova-Repic, C Machacek, GJL Bernardes, A Moreira, H Stockinger, M Burnet, AM Carmo, AC Gomes, A Preto, G Bismuth, A Cavaco-Paulo
– J Biomed Nanotechnol
(2015)
11,
2243
Site-selective protein-modification chemistry for basic biology and drug development
N Krall, FP da Cruz, O Boutureira, GJL Bernardes
– Nat Chem
(2015)
8,
102
Sulfur-Limonene Polysulfide: A Material Synthesized Entirely from Industrial By-Products and Its Use in Removing Toxic Metals from Water and Soil.
MP Crockett, AM Evans, MJH Worthington, IS Albuquerque, AD Slattery, CT Gibson, JA Campbell, DA Lewis, GJL Bernardes, JM Chalker
– Angewandte Chemie International Edition
(2015)
55,
1714
An N-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species
JD Seixas, M Chaves-Ferreira, D Montes-Grajales, AM Gonçalves, AR Marques, LM Saraiva, J Olivero-Verbel, CC Romão, GJL Bernardes
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2015)
21,
14708
Peptide Anchor for Folate-Targeted Liposomal Delivery
E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJL Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JPFC Rossi, AC Gomes, A Preto, A Cavaco-Paulo
– Biomacromolecules
(2015)
16,
2904
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana
– Angewandte Chemie International Edition
(2015)
54,
9830
Size controlled protein nanoemulsions for active targeting of folate receptor positive cells
A Loureiro, E Nogueira, NG Azoia, MP Sárria, AS Abreu, U Shimanovich, A Rollett, J Härmark, H Hebert, G Guebitz, GJL Bernardes, A Preto, AC Gomes, A Cavaco-Paulo
– Colloids and surfaces. B, Biointerfaces
(2015)
135,
90
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody.
N Martínez-Sáez, J Castro-López, J Valero-González, D Madariaga, I Compañón, VJ Somovilla, M Salvadó, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana
– Angewandte Chemie (International ed. in English)
(2015)
54,
9830
Synthesis of Fluorosugar Reagents for the Construction of Well-Defined Fluoroglycoproteins
M Salvadó, B Amgarten, S Castillón, GJL Bernardes, O Boutureira
– Organic letters
(2015)
17,
2836
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation
E Lira-Navarrete, M de Las Rivas, I Compañón, MC Pallarés, Y Kong, J Iglesias-Fernández, GJL Bernardes, JM Peregrina, C Rovira, P Bernadó, P Bruscolini, H Clausen, A Lostao, F Corzana, R Hurtado-Guerrero
– Nat Commun
(2015)
6,
6937