skip to content

Yusuf Hamied Department of Chemistry

 
Identification of Intrinsic Drug Resistance and Its Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens.
I Ayestaran, A Galhoz, E Spiegel, B Sidders, JR Dry, F Dondelinger, A Bender, U McDermott, F Iorio, MP Menden
– Patterns (N Y)
(2020)
1,
100065
Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports
I Smit, A Afzal, C Allen, F Svensson, T Hanser, A Bender
(2020)
2020.06.12.135939
QSAR-derived affinity fingerprints (part 2): modeling performance for potency prediction.
I Cortés-Ciriano, C Škuta, A Bender, D Svozil
– Journal of cheminformatics
(2020)
12,
41
QSAR-derived affinity fingerprints (part 1): Fingerprint construction and modeling performance for similarity searching, bioactivity classification and scaffold hopping
C Škuta, I Cortés-Ciriano, W Dehaen, P Kříž, GJP van Westen, IV Tetko, A Bender, D Svozil
– J Cheminform
(2020)
12,
39
Neurochemical underpinning of hemodynamic response to neuropsychiatric drugs: A meta- and cluster analysis of preclinical studies.
LH Mervin, E Mitricheva, NK Logothetis, A Bifone, A Bender, HR Noori
– Journal of Cerebral Blood Flow & Metabolism
(2020)
41,
874
EMDIP: An Entropy Measure to Discover Important Proteins in PPI networks
H Bashiri, H Rahmani, V Bashiri, D Módos, A Bender
– Computers in Biology and Medicine
(2020)
120,
103740
Establishing GPCR Targets of hMAO Active Anthraquinones from <i>Cassia obtusifolia</i> Linn Seeds Using <i>In Silico</i> and <i>In Vitro</i> Methods
P Paudel, SH Seong, FM Fauzi, A Bender, HA Jung, JS Choi
– ACS Omega
(2020)
5,
7705
Prediction and mechanistic analysis of Drug-Induced Liver Injury (DILI) based on chemical structure
A Liu, M Walter, P Wright, AM Bartosik, D Dolciami, A Elbasir, H Yang, A Bender
(2020)
Bioinformatic Approaches in the Understanding of Mechanism of Action (MoA)
M-A Trapotsi, I Barrett, O Engkvist, A Bender
(2020)
323
THE APPLICATION OF ITERATIVE SCREENING TO HIT IDENTIFICATION
F Svensson, A Bender, U Norinder
(2020)
315
Integrated network analysis using patient-specific single-nucleotide polymorphism profiles uncovers new pathways involved in ulcerative colitis pathogenesis
D Modos, J Brooks, P Sudhakar, B Verstockt, B Alexander-Dann, A Zoufir, D Fazekas, S Vermeire, T Korcsmaros, A Bender
– JOURNAL OF CROHNS & COLITIS
(2020)
14,
S092
Chapter 5 Concepts and Applications of Conformal Prediction in Computational Drug Discovery
I Cortés-Ciriano, A Bender
(2020)
63
INTEGRATED NETWORK ANALYSIS USING PATIENT-SPECIFIC SINGLE NUCLEOTIDE POLYMORPHISM PROFILES UNCOVERS NEW PATHWAYS INVOLVED IN ULCERATIVE COLITIS PATHOGENESIS
D Modos, J Brooks, P Sudhakar, B Verstockt, B Alexander-Dann, A Zoufir, D Fazekas, S Carding, S Vermeire, A Bender, T Korcsmaros
– GASTROENTEROLOGY
(2020)
158,
S795
Structural Chemogenomics Profiling Protein-Ligand Interactions in Polypharmacological Space
B Briels, C De Graaf, A Bender
(2020)
53
Drug Combination Modeling
AHC Vlot, DJ Mason, KC Bulusu, A Bender
(2020)
1-3,
269
Understanding Conditional Associations between ToxCast in Vitro Readouts and the Hepatotoxicity of Compounds Using Rule-Based Methods.
SY Mahmoud, F Svensson, A Zoufir, D Módos, AM Afzal, A Bender
– Chemical Research in Toxicology
(2019)
33,
137
Applying synergy metrics to combination screening data: agreements, disagreements and pitfalls.
AHC Vlot, N Aniceto, MP Menden, G Ulrich-Merzenich, A Bender
– Drug discovery today
(2019)
24,
2286
Triazole‐Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells
HK Keerthy, S Mohan, Basappa, H Bharathkumar, S Rangappa, F Svensson, A Bender, CD Mohan, KS Rangappa, R Bhatnagar
– Chem Biodivers
(2019)
16,
e1900234
Elucidating Compound Mechanism of Action and Predicting Cytotoxicity Using Machine Learning Approaches, Taking Prediction Confidence into Account.
G Drakakis, I Cortés-Ciriano, B Alexander-Dann, A Bender
– Current Protocols in Chemical Biology
(2019)
11,
e73
Concepts and Applications of Conformal Prediction in Computational Drug Discovery
I Cortés-Ciriano, A Bender
(2019)