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Yusuf Hamied Department of Chemistry

 

Publications by Professor Andreas Bender

Use of ligand based models for protein domains to predict novel molecular targets and applications to triage affinity chromatography data.
A Bender, D Mikhailov, M Glick, J Scheiber, JW Davies, S Cleaver, S Marshall, JA Tallarico, E Harrington, I Cornella-Taracido, JL Jenkins
– J Proteome Res
(2009)
8,
2575
(DOI: 10.1021/pr900107z)
The discovery of antibacterial agents using diversity-oriented synthesis
WRJD Galloway, A Bender, M Welch, DR Spring
– Chemical communications (Cambridge, England)
(2009)
2446
(DOI: 10.1039/b816852k)
Substructure Mining of GPCR Ligands Reveals Activity-Class Specific Functional Groups in an Unbiased Manner
E van der Horst, Y Okuno, A Bender, AP Ijzerman
– J Chem Inf Model
(2009)
49,
348
(DOI: 10.1021/ci8003896)
Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis.
J Scheiber, B Chen, M Milik, SCK Sukuru, A Bender, D Mikhailov, S Whitebread, J Hamon, K Azzaoui, L Urban, M Glick, JW Davies, JL Jenkins
– Journal of chemical information and modeling
(2009)
49,
308
(DOI: 10.1021/ci800344p)
Substructure mining of GPCR ligands reveals activity-class specific functional groups in an unbiased manner.
E van der Horst, Y Okuno, A Bender, AP IJzerman
– Journal of chemical information and modeling
(2009)
49,
348
(DOI: 10.1021/ci8003896)
Characterization of Activity Landscapes Using 2D and 3D Similarity Methods: <i>Consensus Activity Cliffs</i>
JL Medina-Franco, K Martínez-Mayorga, A Bender, RM Marín, MA Giulianotti, C Pinilla, RA Houghten
– Journal of chemical information and modeling
(2009)
49,
477
(DOI: 10.1021/ci800379q)
Gaining Insight into Off-Target Mediated Effects of Drug Candidates with a Comprehensive Systems Chemical Biology Analysis
J Scheiber, B Chen, M Milik, SC Sukuru, A Bender, D Mikhailov, S Whitebread, J Hamon, K Azzaoui, L Urban, M Glick, JW Davies, JL Jenkins
– Journal of Chemical Information and Modeling
(2009)
49,
308
(DOI: 10.1021/ci800344p)
How Similar Are Similarity Searching Methods? A Principal Component Analysis of Molecular Descriptor Space
A Bender, JL Jenkins, J Scheiber, SCK Sukuru, M Glick, JW Davies
– Journal of chemical information and modeling
(2009)
49,
108
(DOI: 10.1021/ci800249s)
Computational methods to support high-content screening: from compound selection and data analysis to postulating target hypotheses
A Kümmel, D Gabriel, CN Parker, A Bender
– Expert opinion on drug discovery
(2008)
4,
5
(DOI: 10.1517/17460440802586434)
Ligand-Target Prediction Using Winnow and Naive Bayesian Algorithms and the Implications of Overall Performance Statistics
F Nigsch, A Bender, JL Jenkins, JBO Mitchell
– Journal of chemical information and modeling
(2008)
48,
2313
(DOI: 10.1021/ci800079x)
Ultra Wideband AGC and VGA designs for Software Radio Applications
P Chopra, N Kumar, R Paily
– TENCON 2008 - 2008 IEEE Region 10 Conference
(2008)
1
(DOI: 10.1109/tencon.2008.4766770)
COMP 86-"Virtual Fragment Linking": An approach to identify potent binders from low affinity fragment hits
TJ Crisman, A Bender, M Milik, JL Jenkins, J Scheiber, SCK Sukuru, J Fejzo, U Hommel, JW Davies, M Glick
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2008)
236,
Diversity‐oriented synthesis
RJ Spandl, M Díaz-Gavilán, KMG O'Connell, GL Thomas, DR Spring
– Chemical record (New York, N.Y.)
(2008)
8,
129
(DOI: 10.1002/tcr.20144)
Which aspects of HTS are empirically correlated with downstream success?
A Bender, D Bojanic, JW Davies, TJ Crisman, D Mikhailov, J Scheiber, JL Jenkins, Z Deng, WAG Hill, M Popov, E Jacoby, M Glick
– Current Opinion in Drug Discovery and Development
(2008)
11,
327
Distributed chemical computing using ChemStar: An open source java remote method invocation architecture applied to large scale molecular data from PubChem
M Karthikeyan, S Krishnan, AK Pandey, A Bender, A Tropsha
– Journal of chemical information and modeling
(2008)
48,
691
(DOI: 10.1021/ci700334f)
“Virtual Fragment Linking”: An Approach To Identify Potent Binders from Low Affinity Fragment Hits
TJ Crisman, A Bender, M Milik, JL Jenkins, J Scheiber, SCK Sukuru, J Fejzo, U Hommel, JW Davies, M Glick
– Journal of medicinal chemistry
(2008)
51,
2481
(DOI: 10.1021/jm701314u)
Anti‐MRSA Agent Discovery Using Diversity‐Oriented Synthesis
GL Thomas, RJ Spandl, FG Glansdorp, M Welch, A Bender, J Cockfield, JA Lindsay, C Bryant, DFJ Brown, O Loiseleur, H Rudyk, M Ladlow, DR Spring
– Angewandte Chemie (International ed. in English)
(2008)
47,
2808
(DOI: 10.1002/anie.200705415)
Diversity-oriented synthesis; A spectrum of approaches and results
RJ Spandl, A Bender, DR Spring
– Organic and Biomolecular Chemistry
(2008)
6,
1149
(DOI: 10.1039/b719372f)
A Scenario Implementation in R for SubtypeDiscovery Examplified on Chemoinformatics Data
F Colas, I Meulenbelt, JJ Houwing-Duistermaat, M Kloppenburg, I Watt, SM Van Rooden, M Visser, J Marinus, EO Cannon, A Bender, JJ Van Hilten, PE Slagboom, JN Kok
– Communications in Computer and Information Science
(2008)
17 CCIS,
669
(DOI: 10.1007/978-3-540-88479-8_48)
Integrating high-content screening and ligand-target prediction to identify mechanism of action.
DW Young, A Bender, J Hoyt, E McWhinnie, G-W Chirn, CY Tao, JA Tallarico, M Labow, JL Jenkins, TJ Mitchison, Y Feng
– Nature chemical biology
(2007)
4,
59
(DOI: 10.1038/nchembio.2007.53)

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