Yusuf Hamied Department of Chemistry

Dr Zenon Toprakcioglu

Research Associate

Publications

Melanin Suppresses Aβ Aggregation and Toxicity
A Röntgen, JL Heise, M Vendruscolo, Z Toprakcioglu
(2026)
(doi: 10.64898/2026.09.01.748646)
Low-abundance αSyn-112 promotes αSyn-140 aggregation in vitro and forms immunoreactive deposits in Parkinson’s disease brain tissue
A Röntgen, G Fusco, J Breiter, JS Beckwith, J Lachica, CE Toomey, J Singh, O Klementieva, S Gandhi, S Lee, A De Simone, Z Toprakcioglu, M Vendruscolo
(2026)
(doi: 10.64898/2026.07.05.736591)
Reversibility and β-sheet formation are decoupled in tau condensate aging
CM Fischer, IA Edu, T Šneideris, I Baronaite, Z Toprakcioglu, L-T Deck, D Qian, R Scrutton, L Dreyer, J Wen, DE Otzen, S Wu, S Perrett, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2026)
123
(doi: 10.1073/pnas.2522993123)
Biomaterials with droplet microfluidics
Y Ou, Z Han, S Cai, JR Heck, Z Toprakcioglu, Z Yu, DA Weitz, TPJ Knowles
Nature Reviews Bioengineering
(2026)
4
(doi: 10.1038/s44222-025-00389-0)
The Liquid State of RIM1α and RBP Condensates is Maintained by Lipids
CM Fischer, Z Toprakcioglu, E de Csilléry, GS Kaminski Schierle, TPJ Knowles
ACS Nano
(2025)
19
(doi: 10.1021/acsnano.5c07661)
Optofluidic Waveguides for the Label-Free Study of Silk Protein Aggregates
JR Heck, Z Toprakcioglu, TE Naegele, MH Frosz, TPJ Knowles, TG Euser
ACS omega
(2025)
10
(doi: 10.1021/acsomega.5c07826)
Recruitment of Aβ into α-Synuclein Condensates Catalyzes Primary Nucleation of α-Synuclein Aggregation
OM Morris, A Röntgen, Z Toprakcioglu, M Cali, S Dada, M Vendruscolo
ACS Cent Sci
(2025)
11
(doi: 10.1021/acscentsci.5c00614)
Aβ42 promotes the aggregation of α-synuclein splice isoforms via heterogeneous nucleation
A Röntgen, Z Toprakcioglu, M Vendruscolo
FEBS Letters
(2025)
599
(doi: 10.1002/1873-3468.70118)
Transcript Identification Using Arrayed Hydrogels with TrapFISH
DB Morse, Z Toprakcioglu, A Denduluri-Marthi, JD Brenton, CJ Thomas, TPJ Knowles
Adv Mater Technol
(2025)
10
(doi: 10.1002/admt.202401953)
Aggregation of α-synuclein splice isoforms through a phase separation pathway
A Roentgen, Z Toprakcioglu, ST Dada, OM Morris, TPJ Knowles, M Vendruscolo
Science Advances
(2025)
11
(doi: 10.1126/sciadv.adq5396)

Research Groups

Telephone number

01223 763845 (shared), 01223 763842

Email address

zt231@cam.ac.uk

College

Pembroke College
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge