Matthew Wheeler

Publications

Accessing iridium Cp* as a cofactor for artificial metalloenzymes

OJ Klein, A Albert-Flores, MG Wheeler, K Rojales, AD Bond, SR Boss, PD Barker

– Journal of inorganic biochemistry

(2025)

265,

112820

(doi: 10.1016/j.jinorgbio.2024.112820)

Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1

SCC Lucas, AG Milbradt, JH Blackwell, S Bonomo, A Brierley, DJ Cassar, J Freeman, TE Hadfield, LA Morrill, R Riemens, S Sarda, S Schiesser, D Wiktelius, S Ahmed, MJ Bostock, U Börjesson, C De Fusco, C Guerot, D Hargreaves, S Hewitt, ML Lamb, N Su, R Whatling, M Wheeler, JG Kettle

– J Med Chem

(2024)

67,

11209

(doi: 10.1021/acs.jmedchem.4c00781)

Fragment-Based Discovery of Novel MUS81 Inhibitors

GW Collie, U Börjesson, Y Chen, Z Dong, P Di Fruscia, A Gohlke, A Hoyle, TA Hunt, MH Jesani, H Luo, J Luptak, AG Milbradt, P Narasimhan, M Packer, S Patel, J Qiao, RI Storer, CJ Stubbs, J Tart, C Truman, AT Wang, MG Wheeler, J Winter-Holt

– ACS medicinal chemistry letters

(2024)

15,

1151

(doi: 10.1021/acsmedchemlett.3c00453)

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