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Yusuf Hamied Department of Chemistry

 

Dr Georg Krainer

Research Associate

Publications

Uncertainty in protein-ligand binding constants: asymmetric confidence intervals versus standard errors.
V Paketurytė, V Petrauskas, A Zubrienė, O Abian, M Bastos, W-Y Chen, MJ Moreno, G Krainer, V Linkuvienė, A Sedivy, A Velazquez-Campoy, MA Williams, D Matulis
– Eur Biophys J
(2021)
50,
661
(doi: 10.1007/s00249-021-01518-4)
Learning the molecular grammar of protein condensates from sequence determinants and embeddings.
KL Saar, AS Morgunov, R Qi, WE Arter, G Krainer, AA Lee, TPJ Knowles
– Proceedings of the National Academy of Sciences
(2021)
118,
e2019053118
(doi: 10.1073/pnas.2019053118)
Chaperones Skp and SurA dynamically expand unfolded outer membrane protein X and synergistically disassemble oligomeric aggregates
N Chamachi, A Hartmann, MQ Ma, G Krainer, M Schlierf
(2021)
2021.02.23.432414
(doi: 10.1101/2021.02.23.432414)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
– Nature Communications
(2021)
12,
1085
(doi: 10.1038/s41467-021-21181-9)
Direct Digital Sensing of Proteins in Solution through Single-Molecule Optofluidics
G Krainer, KL Saar, WE Arter, TPJ Knowles
– Biophysical Journal
(2021)
120,
114A
(doi: 10.1016/j.bpj.2020.11.2269)
Interactions of α-synuclein oligomers with lipid membranes.
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
– Biochim Biophys Acta Biomembr
(2020)
1863,
183536
(doi: 10.1016/j.bbamem.2020.183536)
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
F Geiger, G Papa, W Arter, J Acker, K Saar, N Erkamp, R Qi, J Bravo, S Strauss, G Krainer, O Burrone, R Jungmann, TPJ Knowles, H Engelke, A Borodavka
(2020)
2020.12.18.423429
(doi: 10.1101/2020.12.18.423429)
Construction of a liquid-liquid phase separation system from the gel-sol transition of elongated protein microgels in a crowding agent
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, T Knowles
(2020)
2020.12.08.416867
(doi: 10.1101/2020.12.08.416867)
The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril Ends
M Schneider, S Gautam, T Herling, E Andrzejewska, G Krainer, A Miller, Q Peter, FS Ruggeri, M Vendruscolo, A Bracher, C Dobson, U Hartl, T Knowles
(2020)
2020.11.02.365825
(doi: 10.1101/2020.11.02.365825)
Machine learning models for predicting protein condensate formation from sequence determinants and embeddings
K Saar, A Morgunov, R Qi, W Arter, G Krainer, A Lee, T Knowles
(2020)
2020.10.26.354753
(doi: 10.1101/2020.10.26.354753)
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Research Group

Email address

gk422@cam.ac.uk

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