Daniel Heraghty

My research focuses on investigating the mechanisms that underlie the initiation of signalling by immune receptors. Prior to joining the Klenerman lab, I completed my undergraduate degree in Natural Sciences at the University of Cambridge. I spent my final year in the Department of Pathology, specialising in Immunology.

Publications

PD-1 signaling and PD-1 blockade-mediated tumor control are established at microvillar T cell contacts.

E Jenkins, M Fellermeyer, DF Heraghty, S Sharma, T Mitra, M Kotowski, J Clarke, Y Lui, S Daly, Z Marin, D Banik, M Körbel, EZQ Ng, T Lister, AM Santos, SF Lee, ML Dustin, SJ Davis, D Klenerman

Science immunology

(2026)

eadz4983

(doi: 10.1126/sciimmunol.adz4983)

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

D Banik, CJ Ward, S Chakraborty, Z Zhang, D Heraghty, P Suresh, B Li, S Kedia, J Pramanik, SJ Davis, JP Roy, MA Chapman, B Mahata, D Klenerman

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

(2026)

e09762

(doi: 10.1002/advs.202509762)

Patch deconvolution for Fourier light-field microscopy.

B Fu, CL Jones, D Heraghty, S Yang, C O'Brien-Ball, V Junghans, H Yang, D Klenerman, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee

Biophys J

(2026)

125

1305

(doi: 10.1016/j.bpj.2026.01.034)

Patch deconvolution for Fourier light-field microscopy

B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee

(2025)

(doi: 10.1101/2025.06.13.659385)

Daniel Heraghty

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Research at Cambridge