Yusuf Hamied Department of Chemistry

Daniel Heraghty

My research focuses on investigating the mechanisms that underlie the initiation of signalling by immune receptors. Prior to joining the Klenerman lab, I completed my undergraduate degree in Natural Sciences at the University of Cambridge. I spent my final year in the Department of Pathology, specialising in Immunology.

Publications

PD-1 signaling and PD-1 blockade-mediated tumor control are established at microvillar T cell contacts.
E Jenkins, M Fellermeyer, DF Heraghty, S Sharma, T Mitra, M Kotowski, J Clarke, Y Lui, S Daly, Z Marin, D Banik, M Körbel, EZQ Ng, T Lister, AM Santos, SF Lee, ML Dustin, SJ Davis, D Klenerman
Sci Immunol
(2026)
11
(doi: 10.1126/sciimmunol.adz4983)
Enzymatic Remodelling of Tumour Microenvironment Enhances Anti-CEACAM5 CAR T-Cell Efficacy Against Colorectal Cancer.
D Banik, CJ Ward, S Chakraborty, Z Zhang, D Heraghty, P Suresh, B Li, S Kedia, J Pramanik, SJ Davis, JP Roy, MA Chapman, B Mahata, D Klenerman
Advanced Science
(2026)
13
(doi: 10.1002/advs.202509762)
Patch deconvolution for Fourier light-field microscopy.
B Fu, CL Jones, D Heraghty, S Yang, C O'Brien-Ball, V Junghans, H Yang, D Klenerman, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2026.01.034)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
(2025)
(doi: 10.1101/2025.06.13.659385)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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