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Yusuf Hamied Department of Chemistry

 

Postdoctoral Research Associate

Publications

Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells
JC Sang, E Hidari, G Meisl, RT Ranasinghe, MG Spillantini, D Klenerman
– Commun Biol
(2021)
4,
613
α-Synuclein strains target distinct brain regions and cell types.
A Lau, RWL So, HHC Lau, JC Sang, A Ruiz-Riquelme, SC Fleck, E Stuart, S Menon, NP Visanji, G Meisl, R Faidi, MM Marano, C Schmitt-Ulms, Z Wang, PE Fraser, A Tandon, BT Hyman, H Wille, M Ingelsson, D Klenerman, JC Watts
– Nat Neurosci
(2019)
23,
21
Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species.
JC Sang, J-E Lee, AJ Dear, S De, G Meisl, AM Thackray, R Bujdoso, TPJ Knowles, D Klenerman
– Chemical science
(2019)
10,
4588
Filamentous aggregates are fragmented by the proteasome holoenzyme
R Cliffe, JC Sang, F Kundel, D Finley, D Klenerman, Y Ye
– Cell Reports
(2019)
26,
2140
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale.
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
– Nano Letters
(2018)
18,
7494
Direct Observation of Murine Prion Protein Replication in Vitro.
JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman
– Journal of the American Chemical Society
(2018)
140,
14789
Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein
M Iljina, L Tosatto, ML Choi, JC Sang, Y Ye, CD Hughes, CE Bryant, S Gandhi, D Klenerman
– Sci Rep
(2016)
6,
33928
Revealing Structural Changes of Prion Protein during Conversion from α‑Helical Monomer to β‑Oligomers by Means of ESR and Nanochannel Encapsulation
C Yang, W-L Lo, Y-H Kuo, JC Sang, C-Y Lee, Y-W Chiang, RP-Y Chen
– ACS chemical biology
(2014)
10,
493
Slow spontaneous α-to-β structural conversion in a non-denaturing neutral condition reveals the intrinsically disordered property of the disulfide-reduced recombinant mouse prion protein
JC Sang, C-Y Lee, FY Luh, Y-W Huang, Y-W Chiang, RP-Y Chen
– Prion
(2012)
6,
489

Research Group

Telephone number

01223 336536 (shared)

Email address

cs783@cam.ac.uk

College

Hughes Hall