Yusuf Hamied Department of Chemistry

Publications by Professor Sir Alan Fersht FRS

Experimental assignment of the structure of the transition state for the association of barnase and barstar.
C Frisch, AR Fersht, G Schreiber
Journal of Molecular Biology
(2001)
308
(doi: 10.1006/jmbi.2001.4577)
Structure of the C-terminal sterile alpha-motif (SAM) domain of human p73 alpha.
WK Wang, M Bycroft, NW Foster, AM Buckle, AR Fersht, YW Chen
Acta Crystallogr D Biol Crystallogr
(2001)
57
(doi: 10.1107/s0907444901002529)
Protein folding from a highly disordered denatured state: the folding pathway of chymotrypsin inhibitor 2 at atomic resolution.
SL Kazmirski, KB Wong, SM Freund, YJ Tan, AR Fersht, V Daggett
Proceedings of the National Academy of Sciences of the United States of America
(2001)
98
(doi: 10.1073/pnas.071054398)
Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography.
MM Altamirano, A Woolfson, A Donda, A Shamshiev, L Briseño-Roa, NW Foster, DB Veprintsev, G De Libero, AR Fersht, C Milstein
Proceedings of the National Academy of Sciences of the United States of America
(2001)
98
(doi: 10.1073/pnas.041596598)
The binding of bis-ANS to the isolated GroEL apical domain fragment induces the formation of a folding intermediate with increased hydrophobic surface not observed in tetradecameric GroEL.
AL Smoot, M Panda, BT Brazil, AM Buckle, AR Fersht, PM Horowitz
Biochemistry
(2001)
40
(doi: 10.1021/bi001822b)
Preface
CM Dobson, R John Ellis, AR Fersht
Philosophical Transactions of the Royal Society B Biological Sciences
(2001)
356
(doi: 10.1098/rstb.2000.0757)
Protein folding and unfolding in microseconds to nanoseconds by experiment and simulation (vol 97, pg 13518, 2000)
U Mayor, CM Johnson, V Daggett, AR Fersht
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2001)
98
Structure on the Move
WA Hendrickson, C-I Brändén, AR Fersht
Structure
(2001)
9
(doi: 10.1016/S0969-2126(00)00562-1)
From minichaperone to GroEL 2: importance of avidity of the multisite ring structure.
J Chatellier, F Hill, AR Fersht
Journal of molecular biology
(2000)
304
(doi: 10.1006/jmbi.2000.4277)
From Minichaperone to GroEL 3: Properties of an Active Single-ring Mutant of GroEL
J Chatellier, F Hill, NW Foster, P Goloubinoff, AR Fersht
J Mol Biol
(2000)
304
(doi: 10.1006/jmbi.2000.4278)
From minichaperone to GroEL 1: information on GroEL-polypeptide interactions from crystal packing of minichaperones.
Q Wang, AM Buckle, AR Fersht
Journal of molecular biology
(2000)
304
(doi: 10.1006/jmbi.2000.4276)
A kinetically significant intermediate in the folding of barnase
AR Fersht
Proceedings of the National Academy of Sciences
(2000)
97
(doi: 10.1073/pnas.260502597)
Protein folding and unfolding in microseconds to nanoseconds by experiment and simulation.
U Mayor, CM Johnson, V Daggett, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2000)
97
(doi: 10.1073/pnas.250473497)
Biophysical characterization of elongin C from Saccharomyces cerevisiae (vol 39, pg 11137, 2000)
A Buchberger, MJ Howard, SMV Freund, M Proctor, PJG Butler, AR Fersht, M Bycroft
BIOCHEMISTRY-US
(2000)
39
(doi: 10.1021/bi005115u)
The deleterious effect of polyglutamine aggregation in cell models of Huntington's disease.
DC Rubinsztein, J Carmichael, J Rankin, J Chatellier, A Woolfson, A Wyttenbach, C Milstein, AR Fersht
AMERICAN JOURNAL OF HUMAN GENETICS
(2000)
67
Elucidating the mechanism of familial amyloidosis- Finnish type: NMR studies of human gelsolin domain 2.
SL Kazmirski, MJ Howard, RL Isaacson, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2000)
97
(doi: 10.1073/pnas.180310097)
Conversion of two-state to multi-state folding kinetics on fusion of two protein foldons.
K Inaba, N Kobayashi, AR Fersht
Journal of Molecular Biology
(2000)
302
(doi: 10.1006/jmbi.2000.4024)
Biophysical characterization of elongin C from Saccharomyces cerevisiae
A Buchberger, MJ Howard, SM Freund, M Proctor, PJ Butler, AR Fersht, M Bycroft
Biochemistry
(2000)
39
(doi: 10.1021/bi0008231)
Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of huntington's disease
J Carmichael, J Chatellier, A Woolfson, C Milstein, AR Fersht, DC Rubinsztein
Proceedings of the National Academy of Sciences of the United States of America
(2000)
97
(doi: 10.1073/pnas.170280697)
Protein Folding Transition States: Elicitation of Hammond Effects by 2,2,2‐Trifluoroethanol
CP Yiu, MG Mateu, AR Fersht
Chembiochem : a European journal of chemical biology
(2000)
1
(doi: 10.1002/1439-7633(20000703)1:1<49::AID-CBIC49>3.0.CO;2-A)
Yusuf Hamied Department of Chemistry
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