Publications by Professor Sir Alan Fersht FRS | Yusuf Hamied Department of Chemistry

Folding of circular and permuted chymotrypsin inhibitor 2: retention of the folding nucleus.

DE Otzen, AR Fersht

Biochemistry

(1998)

37

8139

(doi: 10.1021/bi980250g)

Characterization of residual structure in the thermally denatured state of barnase by simulation and experiment: Description of the folding pathway (vol 94, pg 13409, 1997)

CJ Bond, KB Wong, J Clarke, AR Fersht, V Daggett

P NATL ACAD SCI USA

(1998)

95

5841

A Search for Single Substitutions That Eliminate Enzymatic Function in a Bacterial Ribonuclease †

DD Axe, NW Foster, AR Fersht

Biochemistry

(1998)

37

7157

(doi: 10.1021/bi9804028)

Research: Protein structure - Sieves in sequence

AR Fersht

SCIENCE

(1998)

280

541

(doi: 10.1126/science.280.5363.541)

The changing nature of the protein folding transition state: Implications for the shape of the free-energy profile for folding

M Oliveberg, YJ Tan, M Silow, AR Fersht

Journal of Molecular Biology

(1998)

277

933

(doi: 10.1006/jmbi.1997.1612)

Movement of the intermediate and rate determining transition state of barnase on the energy landscape with changing temperature.

PA Dalby, M Oliveberg, AR Fersht

Biochemistry

(1998)

37

4674

(doi: 10.1021/bi972798d)

Folding intermediates of wild-type and mutants of barnase. I. Use of phi-value analysis and m-values to probe the cooperative nature of the folding pre-equilibrium.

PA Dalby, M Oliveberg, AR Fersht

Journal of molecular biology

(1998)

276

625

(doi: 10.1006/jmbi.1997.1546)

Folding intermediates of wild-type and mutants of barnase. II. Correlation of changes in equilibrium amide exchange kinetics with the population of the folding intermediate

PA Dalby, J Clarke, CM Johnson, AR Fersht

J Mol Biol

(1998)

276

647

(doi: 10.1006/jmbi.1997.1547)

Real-time NMR studies on folding of mutants of barnase and chymotrypsin inhibitor 2

TR Killick, SM Freund, AR Fersht

FEBS Lett

(1998)

423

110

(doi: 10.1016/S0014-5793(98)00075-1)

Thermodynamic stability and folding of GroEL minichaperones 1 1Edited by P. E. Wright

R Golbik, R Zahn, SE Harding, AR Fersht

Journal of molecular biology

(1998)

276

505

(doi: 10.1006/jmbi.1997.1538)

Folding and binding - overview

E Shakhnovich, A Fersht

Current Opinion in Structural Biology

(1998)

8

65

(doi: 10.1016/s0959-440x(98)80011-0)

A reply to Englander and Woodward

J Clarke, LS Itzhaki, AR Fersht

Trends in Biochemical Sciences

(1998)

23

379

(doi: 10.1016/s0968-0004(98)01280-8)

Thermodynamic stability of wild-type and mutant p53 core domain.

AN Bullock, J Henckel, BS DeDecker, CM Johnson, PV Nikolova, MR Proctor, DP Lane, AR Fersht

Proc Natl Acad Sci U S A

(1997)

94

14338

(doi: 10.1073/pnas.94.26.14338)

Characterization of residual structure in the thermally denatured state of barnase by simulation and experiment: Description of the folding pathway

CJ Bond, KB Wong, J Clarke, AR Fersht, V Daggett

Proc Natl Acad Sci U S A

(1997)

94

13409

(doi: 10.1073/pnas.94.25.13409)

Strain in the transition state of folding and in the native state of proteins

A Ladurner, L Itzhaki, A Fersht

Protein Engineering

(1997)

10

29

Folding of barnase in the presence of the molecular chaperone SecB

G Stenberg, AR Fersht

Journal of molecular biology

(1997)

274

268

(doi: 10.1006/jmbi.1997.1398)

Glutamine, alanine or glycine repeats inserted into the loop of a protein have minimal effects on stability and folding rates.

AG Ladurner, AR Fersht

Journal of Molecular Biology

(1997)

273

330

(doi: 10.1006/jmbi.1997.1304)

Complementation of peptide fragments of the single domain protein chymotrypsin inhibitor 2

AG Ladurner, LS Itzhaki, G de Prat Gay, AR Fersht

Journal of molecular biology

(1997)

273

317

(doi: 10.1006/jmbi.1997.1303)

Circular dichroism of denatured barstar suggests residual structure

B Nölting, R Golbik, AS Soler-González, AR Fersht

Biochemistry

(1997)

36

9899

(doi: 10.1021/bi962879u)

Hydrogen exchange in chymotrypsin inhibitor 2 probed by mutagenesis.

JL Neira, LS Itzhaki, DE Otzen, B Davis, AR Fersht

Journal of molecular biology

(1997)

270

99

(doi: 10.1006/jmbi.1997.1088)