Mechanism of aminoacylation of transfer RNA. A pre-steady-state analysis of the reaction pathway catalyzed by the methionyl-tRNA synthetase of Bacillus stearothermophilus
Biochemistry
(2002)
17
5591
(doi: 10.1021/bi00619a002)
Ligand binding stoichiometries, subunit structure, and slow transitions in aminoacyl-tRNA synthetases
Biochemistry
(2002)
16
4005
(doi: 10.1021/bi00637a011)
Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing.
Biochemistry
(2002)
15
3342
(doi: 10.1021/bi00660a026)
Active site titration and aminoacyl adenylate binding stoichiometry of aminoacyl-tRNA synthetases
Biochemistry
(2002)
14
1
(doi: 10.1021/bi00672a001)
Demonstration of two active sites on a monomeric aminoacyl-tRNA synthetase. Possible roles of negative cooperativity and half-of-the-sites reactivity in oligomeric enzymes.
Biochemistry
(2002)
14
5
(doi: 10.1021/bi00672a002)
Tyrosyl-tRNA synthetase from Escherichia coli. Stoichiometry of ligand binding and half-of-the-sites reactivity in aminoacylation
Biochemistry
(2002)
14
3344
(doi: 10.1021/bi00686a009)
pH Dependence of chymotrypsin catalysis. Appendix. Substrate binding to dimeric α-chymotrypsin studied by x-ray diffraction and the equilibrium method
Biochemistry
(2002)
13
1416
(doi: 10.1021/bi00704a016)
Influence of globin structure on the state of the heme. II. Allosteric transitions in methemoglobin.
Biochemistry
(2002)
13
2174
(doi: 10.1021/bi00707a027)
Mechanism of chymotrypsin. Structure, reactivity, and nonproductive binding relationships.
Biochemistry
(2002)
12
1067
(doi: 10.1021/bi00730a008)
Demonstration of the acyl-enzyme mechanism for the hydrolysis of peptides and anilides by chymotrypsin
Biochemistry
(2002)
12
2025
(doi: 10.1021/bi00735a001)
Leaving group specificity in the chymotrypsin-catalyzed hydrolysis of peptides. Stereochemical interpretation
Biochemistry
(2002)
12
2035
(doi: 10.1021/bi00735a002)
Anomalous pH dependence of Kcat/Km in enzyme reactions. Rate constants for the association of chymotrypsin with substrates
Biochemistry
(2002)
12
4713
(doi: 10.1021/bi00747a026)
Acetylpyridinium ion intermediate in pyridine-catalyzed hydrolysis and acyl transfer reactions of acetic anhydride. Observation, kinetics, structure-reactivity correlations, and effects of concentrated salt solutions
Journal of the American Chemical Society
(2002)
92
5432
(doi: 10.1021/ja00721a023)
Reactions of nucleophilic reagents with acylating agents of extreme reactivity and unreactivity. Correlation of .beta. values for attacking and leaving group variation
Journal of the American Chemical Society
(2002)
92
5442
(doi: 10.1021/ja00721a024)
Free energies of hydrolysis of amides and peptides in aqueous solution at 25 degrees.
Journal of the American Chemical Society
(2002)
93
3499
(doi: 10.1021/ja00743a034)
Acyl-transfer reactions of amides and esters with alcohols and thiols. A reference system for the serine and cysteine proteinases. Concerning the N protonation of amides and amide-imidate equilibria.
J Am Chem Soc
(2002)
93
3504
(doi: 10.1021/ja00743a035)
Mechanism of the -chymotrypsin-catalyzed hydrolysis of amides. pH dependence of k c and K m . Kinetic detection of an intermediate.
J Am Chem Soc
(2002)
93
7079
(doi: 10.1021/ja00754a066)
Mechanism of the -chymotrypsin-catalyzed hydrolysis of specific amide substrates.
Journal of the American Chemical Society
(2002)
94
293
(doi: 10.1021/ja00756a061)
Stability and folding of the protein complexes of barnase
Eur J Biochem
(2002)
267
2859
Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid β-peptide of amyloid plaques
Proceedings of the National Academy of Sciences of the United States of America
(2002)
99
5596
(doi: 10.1073/pnas.042681599)
