Backbone dynamics of chymotrypsin inhibitor 2: effect of breaking the active site bond and its implications for the mechanism of inhibition of serine proteases.
Biochemistry
(2002)
34
2225
(doi: 10.1021/bi00007a017)
Protein fragments as models for events in protein folding pathways: Protein engineering analysis of the association of two complementary fragments of the barley chymotrypsin inhibitor 2 (CI-2)
Biochemistry
(2002)
34
1695
(doi: 10.1021/bi00005a026)
Analysis of the mechanism of assembly of cleaved barnase from two peptide fragments and its relevance to the folding pathway of uncleaved barnase
Biochemistry
(2002)
34
1464
(doi: 10.1021/bi00004a042)
Leaving group specificity in the chymotrypsin-catalyzed hydrolysis of peptides. Stereochemical interpretation
Biochemistry
(2002)
12
2035
(doi: 10.1021/bi00735a002)
Anomalous pH dependence of Kcat/Km in enzyme reactions. Rate constants for the association of chymotrypsin with substrates
Biochemistry
(2002)
12
4713
(doi: 10.1021/bi00747a026)
Tyrosyl-tRNA synthetase from Escherichia coli. Stoichiometry of ligand binding and half-of-the-sites reactivity in aminoacylation
Biochemistry
(2002)
14
3344
(doi: 10.1021/bi00686a009)
Active site titration and aminoacyl adenylate binding stoichiometry of aminoacyl-tRNA synthetases
Biochemistry
(2002)
14
1
(doi: 10.1021/bi00672a001)
INFLUENCE OF GLOBIN STRUCTURE ON STATE OF HEME .2. ALLOSTERIC TRANSITIONS IN METHEMOGLOBIN
Biochemistry
(2002)
13
2174
(doi: 10.1021/bi00707a027)
DEMONSTRATION OF 2 ACTIVE-SITES ON A MONOMERIC AMINOACYL-TRANSFER-RNA SYNTHETASE - POSSIBLE ROLES OF NEGATIVE COOPERATIVITY AND HALF-OF-SITES REACTIVITY IN OLIGOMERIC ENZYMES
Biochemistry
(2002)
14
5
(doi: 10.1021/bi00672a002)
Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing.
Biochemistry
(2002)
15
3342
(doi: 10.1021/bi00660a026)
Mechanism of chymotrypsin. Structure, reactivity, and nonproductive binding relationships.
Biochemistry
(2002)
12
1067
(doi: 10.1021/bi00730a008)
Mechanism of aminoacylation of transfer RNA. A pre-steady-state analysis of the reaction pathway catalyzed by the methionyl-tRNA synthetase of Bacillus stearothermophilus
Biochemistry
(2002)
17
5591
(doi: 10.1021/bi00619a002)
Ligand binding and enzymic catalysis coupled through subunits in tyrosyl-tRNA synthetase
Biochemistry
(2002)
14
13
(doi: 10.1021/bi00672a003)
Protection of an unstable reaction intermediate examined with linear free energy relationships in tyrosyl-tRNA synthetase.
Biochemistry
(2002)
28
9201
(doi: 10.1021/bi00449a036)
RECOMBINANT CHYMOTRYPSIN INHIBITOR-2 - EXPRESSION, KINETIC-ANALYSIS OF INHIBITION WITH ALPHA-CHYMOTRYPSIN AND WILD-TYPE AND MUTANT SUBTILISIN BPN', AND PROTEIN ENGINEERING TO INVESTIGATE INHIBITORY SPECIFICITY AND MECHANISM
Biochemistry
(2002)
29
7339
(doi: 10.1021/bi00483a025)
Demonstration of the acyl-enzyme mechanism for the hydrolysis of peptides and anilides by chymotrypsin.
Biochemistry
(2002)
12
2025
(doi: 10.1021/bi00735a001)
Mechanism of the -chymotrypsin-catalyzed hydrolysis of specific amide substrates.
Journal of the American Chemical Society
(2002)
94
293
(doi: 10.1021/ja00756a061)
Probing the limits of protein-amino acid side chain recognition with the aminoacyl-tRNA synthetases. Discrimination against phenylalanine by tyrosyl-tRNA synthetases
Biochemistry
(2002)
19
5520
(doi: 10.1021/bi00565a009)
pH Dependence of chymotrypsin catalysis. Appendix. Substrate binding to dimeric α-chymotrypsin studied by x-ray diffraction and the equilibrium method
Biochemistry
(2002)
13
1416
(doi: 10.1021/bi00704a016)
Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis
Biochemistry
(2002)
26
8031
(doi: 10.1021/bi00399a001)
