Engineering enzymes
G Winter, AR Fersht
Trends in Biotechnology
(1984)
2
Fidelity of DNA replication under conditions used for oligodeoxynucleotide-directed mutagenesis
JP Shi, AR Fersht
J Mol Biol
(1984)
177
Basis of biological specificity
AR Fersht
Trends in Biochemical Sciences
(1984)
9
Genetic dissection of tyrosyl-tRNA synthetase
G WINTER, P CARTER, MMY WAYE, DM BLOW, AJ WILKINSON, J-P SHI, AR FERSHT
Biochemical Society Transactions
(1984)
12
A large increase in enzyme-substrate affinity by protein engineering.
AJ Wilkinson, AR Fersht, DM Blow, P Carter, G Winter
Nature
(1984)
307
Fidelity of DNA Replication in Vitro
AR Fersht
Advances in experimental medicine and biology
(1984)
179
REPLICATION OF PHI-X174 DNA BY CALF THYMUS DNA POLYMERASE-ALPHA - MEASUREMENT OF ERROR RATES AT THE AMBER-16 CODON
F Grosse, G Krauss, JW Knill-Jones, AR Fersht
Advances in experimental medicine and biology
(1984)
179
Deletion mutagenesis using an ‘M13 splint’: the N‐terminal structural domain of tyrosyl‐tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate.
MM Waye, G Winter, AJ Wilkinson, AR Fersht
The EMBO Journal
(1983)
2
Accuracy of DNA polymerase-alpha in copying natural DNA.
F Grosse, G Krauss, JW Knill-Jones, AR Fersht
The EMBO journal
(1983)
2
Fidelity of replication of bacteriophage phi X174 DNA in vitro and in vivo.
AR Fersht, JW Knill-Jones
Journal of molecular biology
(1983)
165
Kinetics of base misinsertion by DNA polymerase I of Escherichia coli.
AR Fersht, JP Shi, WC Tsui
Journal of molecular biology
(1983)
165
Contribution of 3′ → 5′ exonuclease activity of DNA polymerase III holoenzyme from Escherichia coli to specificity
AR Fersht, JW Knill-Jones
J Mol Biol
(1983)
165
ACCURACY OF DNA POLYMERASE-ALPHA IN COPYING NATURAL DNA
F GROSSE, G KRAUSS, JW KNILLJONES, AR FERSHT
HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE
(1983)
364
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding.
G Winter, AR Fersht, AJ Wilkinson, M Zoller, M Smith
Nature
(1982)
299
Kinetic basis of spontaneous mutation Misinsertion frequencies, proofreading specificities and cost of proofreading by DNA polymerases of Escherichia coli
AR Fersht, JW Knill-Jones, WC Tsui
J Mol Biol
(1982)
156
Probing the principles of amino acid selection using the alanyl-tRNA synthetase from Escherichia coli
WC Tsui, AR Fersht
Nucleic Acids Research
(1981)
9
Enzymic editing mechanisms and the genetic code.
AR Fersht
Proceedings of the Royal Society of London. Series B, Biological sciences
(1981)
212
Alternative pathways for editing non-cognate amino acids by aminoacyl-tRNA synthetases.
H Jakubowski, AR Fersht
Nucleic Acids Research
(1981)
9
DNA polymerase accuracy and spontaneous mutation rates: frequencies of purine.purine, purine.pyrimidine, and pyrimidine.pyrimidine mismatches during DNA replication.
AR Fersht, JW Knill-Jones
Proceedings of the National Academy of Sciences
(1981)
78
INTRODUCTORY-REMARKS TO THE 3RD SESSION
AR Fersht
Philosophical Transactions of the Royal Society of London. B, Biological Sciences
(1981)
293