Yusuf Hamied Department of Chemistry

Publications by Professor Sir Alan Fersht FRS

The folding of an enzyme
L Serrano, A Matouschek, AR Fersht
Journal of molecular biology
(1992)
224
(doi: 10.1016/0022-2836(92)90566-3)
The folding of an enzyme II. Substructure of barnase and the contribution of different interactions to protein stability
L Serrano, JT Kellis, P Cann, A Matouschek, AR Fersht
Journal of molecular biology
(1992)
224
(doi: 10.1016/0022-2836(92)90562-x)
An N-terminal fragment of barnase has residual helical structure similar to that in a refolding intermediate
J Sancho, JL Neira, AR Fersht
Journal of molecular biology
(1992)
224
(doi: 10.1016/0022-2836(92)90559-3)
Dissection of an enzyme by protein engineering The N and C-terminal fragments of barnase form a native-like complex with restored enzymic activity
J Sancho, AR Fersht
Journal of molecular biology
(1992)
224
(doi: 10.1016/0022-2836(92)90558-2)
Effect of alanine versus glycine in alpha-helices on protein stability.
L Serrano, JL Neira, J Sancho, AR Fersht
Nature
(1992)
356
(doi: 10.1038/356453a0)
<title>Energy transfer and specific fluorescence quenching effects in barnase, studied via multifrequency phase-fluorometry of tryptophan mutants</title>
K Willaert, R Loewenthal, J Sancho, M Froeyen, AR Fersht, Y Engelborghs
SPIE Proceedings
(1992)
1640
(doi: 10.1117/12.58269)
Pathway of protein folding.
AR Fersht, A Matouschek, J Sancho, L Serrano, S Vuilleumier
Faraday Discussions
(1992)
93
(doi: 10.1039/fd9929300183)
General discussion
GE Schulz, LN Johnson, ML Sinnott, M Perutz, SS Taylor, M Karplus, T Ohta, PN Edwards, DM Blow, J Thornton, AR Fersht, A Warshel, AD Buckingham, D Eisenberg, GG Dodson, IH Williams, MCR Symons, BW Matthews, K Wüthrich, L Graf, H Dalton, O Smart, M Rossi, R Lewis
Faraday Discuss.
(1992)
93
(doi: 10.1039/fd9929300195)
General discussion
D Eisenberg, MF Perutz, AD Buckingham, L Graf, J Thornton, DM Blow, AR Fersht, M Karplus, LN Johnson, F Rippmann, GG Dodson, PN Edwards, P Halling, K Wüthrich, MCR Symons, K Marshall, BL Vallee, M Rossi, DS Auld, E Pombo-Villar, ML Sinnott, HBF Dixon, A Berry, DR Brown, JA Littlechild, A Thomson, N Ito, PF Knowles, SS Taylor, GE Schulz, O Misset
Faraday Discuss.
(1992)
93
(doi: 10.1039/FD9929300107)
Mapping transition states of protein unfolding by protein engineering of ligand-binding sites.
J Sancho, EM Meiering, AR Fersht
Journal of molecular biology
(1991)
221
(doi: 10.1016/0022-2836(91)80188-Z)
Surface electrostatic interactions contribute little to stability of barnase
D Sali, M Bycroft, AR Fersht
Journal of molecular biology
(1991)
220
(doi: 10.1016/0022-2836(91)90117-O)
Pathway and stability of protein folding
AR Fersht, M Bycroft, A Horovitz, JT Kellis, A Matouschek, L Serrano
Philosophical Transactions of the Royal Society B Biological Sciences
(1991)
332
(doi: 10.1098/rstb.1991.0046)
COSMIC analysis of the major alpha-helix of barnase during folding.
A Horovitz, L Serrano, AR Fersht
Journal of molecular biology
(1991)
219
(doi: 10.1016/0022-2836(91)90852-W)
Aromatic-aromatic interactions and protein stability
L Serrano, M Bycroft, AR Fersht
Journal of molecular biology
(1991)
218
(doi: 10.1016/0022-2836(91)90725-L)
Linear free energy relationships in enzyme binding interactions studied by protein engineering
AR Fersht, TN Wells
Protein Eng
(1991)
4
(doi: 10.1093/protein/4.3.229)
Protein engineering in analysis of protein folding pathways and stability.
A Matouschek, AR Fersht
Methods Enzymol
(1991)
202
(doi: 10.1016/0076-6879(91)02008-w)
STABILIZATION OF BARNASE BY AN INTERACTION BETWEEN 2 OPPOSITELY CHARGED SIDE-CHAINS
D SALI, M BYCROFT, AR FERSHT
TECHNIQUES IN PROTEIN CHEMISTRY II
(1991)
Strength and co-operativity of contributions of surface salt bridges to protein stability
A Horovitz, L Serrano, B Avron, M Bycroft, AR Fersht
J Mol Biol
(1990)
216
(doi: 10.1016/S0022-2836(99)80018-7)
Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins
A Horovitz, AR Fersht
Journal of Molecular Biology
(1990)
214
(doi: 10.1016/0022-2836(90)90275-q)
Detection and characterization of a folding intermediate in barnase by NMR.
M Bycroft, A Matouschek, JT Kellis, L Serrano, AR Fersht
Nature
(1990)
346
(doi: 10.1038/346488a0)
Yusuf Hamied Department of Chemistry
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