University Professor

Rosana is the Professor of Computational and Molecular Biophysics at the Departments of Chemistry and Genetics, and a Winton Advanced Research Fellow in the Department of Physics. Her group develops multiscale modelling approaches to investigate the physicochemical driving forces that govern DNA packaging inside cells, membraneless compartamentalization via liquid-liquid phase behaviour of biomolecules (proteins, nucleic acids, and chromatin), chromatin structure, epigenetic phenomena, and the relationship between the structure of the genome and gene expression regulation. 

Professor Collepardo discusses her research

Publications

Location and Concentration of Aromatic-Rich Segments Dictates the Percolating Inter-Molecular Network and Viscoelastic Properties of Ageing Condensates.
S Blazquez, I Sanchez-Burgos, J Ramirez, T Higginbotham, MM Conde, R Collepardo-Guevara, AR Tejedor, JR Espinosa
Advanced Science
(2023)
10
Universal predictive scaling laws for phase separation of prion-like low complexity domains
J Joseph, MJ Maristany, AA Gonzalez, R Collepardo-Guevara
(2023)
Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
MJ Maristany, AA Gonzalez, JR Espinosa, J Huertas, R Collepardo-Guevara, JA Joseph
(2023)
Time-Dependent Material Properties of Aging Biomolecular Condensates from Different Viscoelasticity Measurements in Molecular Dynamics Simulations
AR Tejedor, R Collepardo-Guevara, J Ramírez, JR Espinosa
The Journal of Physical Chemistry B
(2023)
127
Theoretical and Data-Driven Approaches for Biomolecular Condensates
KL Saar, D Qian, LL Good, AS Morgunov, R Collepardo-Guevara, RB Best, TPJ Knowles
Chemical Reviews
(2023)
123
Energy landscapes and heat capacity signatures for peptides correlate with phase separation propensity
Nicy, JA Joseph, R Collepardo-Guevara, DJ Wales
(2023)
Aromatic and arginine content drives multiphasic condensation of protein–RNA mixtures
PY Chew, JA Joseph, R Collepardo-Guevara, A Reinhardt
(2023)
Correction to “Photogeneration of Spin Quintet Triplet–Triplet Excitations in DNA-Assembled Pentacene Stacks”
SRE Orsborne, J Gorman, LR Weiss, A Sridhar, NA Panjwani, G Divitini, P Budden, D Palecek, STJ Ryan, A Rao, R Collepardo-Guevara, AH El-Sagheer, T Brown, J Behrends, RH Friend, F Auras
Journal of the American Chemical Society
(2023)
145
Surfactants or scaffolds? RNAs of varying lengths control the thermodynamic stability of condensates differently.
I Sanchez-Burgos, L Herriott, R Collepardo-Guevara, JR Espinosa
Biophysical Journal
(2023)
122
Photogeneration of spin quintet triplet-triplet excitations in DNA-assembled pentacene stacks
SRE Orsborne, J Gorman, LR Weiss, A Sridhar, NA Panjwani, G Divitini, P Budden, D Palecek, STJ Ryan, A Rao, R Collepardo-Guevara, AH El-Sagheer, T Brown, J Behrends, RH Friend, F Auras
J Am Chem Soc
(2023)
145

Research Interest Group

Email address

College