University Professor
Rosana is the Professor of Computational and Molecular Biophysics at the Departments of Chemistry and Genetics, and a Winton Advanced Research Fellow in the Department of Physics. Her group develops multiscale modelling approaches to investigate the physicochemical driving forces that govern DNA packaging inside cells, membraneless compartamentalization via liquid-liquid phase behaviour of biomolecules (proteins, nucleic acids, and chromatin), chromatin structure, epigenetic phenomena, and the relationship between the structure of the genome and gene expression regulation.
Professor Collepardo discusses her research
Publications
Capturing single-molecule properties does not ensure accurate prediction of biomolecular phase diagrams
Molecular Physics
(2024)
122
e2425757
Dynamically arrested condensate fusion creates complex structures with varying material properties
(2024)
(doi: 10.1101/2024.11.15.623768)
Capturing single-molecule properties does not ensure accurate prediction of biomolecular phase diagrams
(2024)
(doi: 10.1101/2024.10.24.619983)
Benchmarking residue-resolution protein coarse-grained models for simulations of biomolecular condensates
(2024)
(doi: 10.1101/2024.08.28.610132)
Chemically-informed coarse-graining of electrostatic forces in charge-rich biomolecular condensates
(2024)
(doi: 10.1101/2024.07.26.605370)
Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
(2024)
(doi: 10.7554/elife.99068.1)
Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation
Cell Reports
(2024)
43
113997
(doi: 10.1016/j.celrep.2024.113997)
Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation.
Cell Rep
(2023)
42
113136
(doi: 10.1016/j.celrep.2023.113136)
Energy Landscapes and Heat Capacity Signatures for Peptides Correlate with Phase Separation Propensity
QRB Discov
(2023)
4
e7
(doi: 10.1017/qrd.2023.5)
Aromatic and arginine content drives multiphasic condensation of protein-RNA mixtures.
Biophysical Journal
(2023)
123
1342
(doi: 10.1016/j.bpj.2023.06.024)
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