Professor of Chemistry & Chemical Biology
Publications
Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity
Cell Rep
(2016)
16
1180
(doi: 10.1016/j.celrep.2016.06.064)
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes
Journal of the American Chemical Society
(2016)
138
718
(doi: 10.1021/jacs.5b07627)
Genetic code expansion in stable cell lines enables encoded chromatin modification.
Nature Methods
(2016)
13
158
(doi: 10.1038/NMETH.3701)
Genetically encoded optical activation of DNA recombination in human cells.
Chemical communications (Cambridge, England)
(2016)
52
8529
(doi: 10.1039/c6cc03934k)
Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation
Journal of Biological Chemistry
(2015)
291
5484
(doi: 10.1074/jbc.M115.707091)
EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling.
Elife
(2015)
4
e12223
(doi: 10.7554/elife.12223)
Ribosome Subunit Stapling for Orthogonal Translation in E. coli
Angew Chem Int Ed Engl
(2015)
54
12791
(doi: 10.1002/anie.201506311)
Ribosome Subunit Stapling for Orthogonal Translation in E. coli
Angewandte Chemie (Weinheim an der Bergstrasse, Germany)
(2015)
127
12982
(doi: 10.1002/ange.201506311)
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog.
Nature Chemical Biology
(2015)
11
496
(doi: 10.1038/nchembio.1823)
Selective, rapid and optically switchable regulation of protein function in live mammalian cells
Nat Chem
(2015)
7
554
(doi: 10.1038/nchem.2253)
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