Professor of Chemistry & Chemical Biology

Publications

Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.
N Huguenin-Dezot, V De Cesare, J Peltier, A Knebel, YA Kristaryianto, DT Rogerson, Y Kulathu, M Trost, JW Chin
Cell Reports
(2016)
16
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes
OS Walker, SJ Elsässer, M Mahesh, M Bachman, S Balasubramanian, JW Chin
J Am Chem Soc
(2016)
138
Genetic code expansion in stable cell lines enables encoded chromatin modification
SJ Elsässer, RJ Ernst, OS Walker, JW Chin
Nature Methods
(2016)
13
Genetically encoded optical activation of DNA recombination in human cells.
J Luo, E Arbely, J Zhang, C Chou, R Uprety, JW Chin, A Deiters
Chem Commun (Camb)
(2016)
52
Structural and mechanistic insights into the regulation of the fundamental Rho regulator RhoGDIα by lysine acetylation
N Kuhlmann, S Wroblowski, P Knyphausen, S de Boor, J Brenig, AY Zienert, K Meyer-Teschendorf, GJK Praefcke, H Nolte, M Krüger, M Schacherl, U Baumann, LC James, JW Chin, M Lammers
The Journal of biological chemistry
(2015)
291
EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling
M Baumdick, Y Brüggemann, M Schmick, G Xouri, O Sabet, L Davis, JW Chin, PIH Bastiaens
eLife
(2015)
4
Ribosome Subunit Stapling for Orthogonal Translation in E. coli
SD Fried, WH Schmied, C Uttamapinant, JW Chin
Angewandte Chemie - International Edition
(2015)
54
Ribosome Subunit Stapling for Orthogonal Translation in E.coli.
SD Fried, WH Schmied, C Uttamapinant, JW Chin
Angew Chem Weinheim Bergstr Ger
(2015)
127
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog.
DT Rogerson, A Sachdeva, K Wang, T Haq, A Kazlauskaite, SM Hancock, N Huguenin-Dezot, MMK Muqit, AM Fry, R Bayliss, JW Chin
Nat Chem Biol
(2015)
11
Selective, rapid and optically switchable regulation of protein function in live mammalian cells.
Y-H Tsai, S Essig, JR James, K Lang, JW Chin
Nature chemistry
(2015)
7

Research Group

Research Interest Group

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