Professor of Chemistry & Chemical Biology

Publications

Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.
OS Walker, SJ Elsässer, M Mahesh, M Bachman, S Balasubramanian, JW Chin
J Am Chem Soc
(2016)
138
Genetic code expansion in stable cell lines enables encoded chromatin modification.
SJ Elsässer, RJ Ernst, OS Walker, JW Chin
Nat Methods
(2016)
13
Genetically encoded optical activation of DNA recombination in human cells
J Luo, E Arbely, J Zhang, C Chou, R Uprety, JW Chin, A Deiters
Chem Commun (Camb)
(2016)
52
Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation
N Kuhlmann, S Wroblowski, P Knyphausen, S de Boor, J Brenig, AY Zienert, K Meyer-Teschendorf, GJK Praefcke, H Nolte, M Krüger, M Schacherl, U Baumann, LC James, JW Chin, M Lammers
J Biol Chem
(2015)
291
EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling.
M Baumdick, Y Brüggemann, M Schmick, G Xouri, O Sabet, L Davis, JW Chin, PIH Bastiaens
eLife
(2015)
4
Ribosome Subunit Stapling for Orthogonal Translation in E. coli.
SD Fried, WH Schmied, C Uttamapinant, JW Chin
Angew Chem Int Ed Engl
(2015)
54
Ribosome Subunit Stapling for Orthogonal Translation in E.  coli.
SD Fried, WH Schmied, C Uttamapinant, JW Chin
Angewandte Chemie (Weinheim an der Bergstrasse, Germany)
(2015)
127
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog
DT Rogerson, A Sachdeva, K Wang, T Haq, A Kazlauskaite, SM Hancock, N Huguenin-Dezot, MMK Muqit, AM Fry, R Bayliss, JW Chin
Nature Chemical Biology
(2015)
11
Selective, rapid and optically switchable regulation of protein function in live mammalian cells
Y-H Tsai, S Essig, JR James, K Lang, JW Chin
Nature chemistry
(2015)
7
Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne
T Machida, K Lang, L Xue, JW Chin, N Winssinger
Bioconjugate chemistry
(2015)
26

Research Group

Research Interest Group

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