Professor of Chemistry & Chemical Biology
Publications
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.
– Scientific Reports
(2017)
7,
39841
(doi: 10.1038/srep39841)
Mitotic phosphorylation of Hsp72 uncouples ATP binding from substrate release and clusters amplified centrosomes in cancer cells.
– MOLECULAR BIOLOGY OF THE CELL
(2017)
28,
Defining synonymous codon compression schemes by genome recoding.
– Nature
(2016)
539,
59
(doi: 10.1038/nature20124)
Genetic code expansion in the mouse brain.
– Nature Chemical Biology
(2016)
12,
776
(doi: 10.1038/nchembio.2160)
Tagging and Enriching Proteins Enables Cell-Specific Proteomics
– Cell Chem Biol
(2016)
23,
805
Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity
– Cell Rep
(2016)
16,
1180
(doi: 10.1016/j.celrep.2016.06.064)
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes
– Journal of the American Chemical Society
(2016)
138,
718
(doi: 10.1021/jacs.5b07627)
Genetic code expansion in stable cell lines enables encoded chromatin modification.
– Nat Methods
(2016)
13,
158
(doi: 10.1038/NMETH.3701)
Genetically encoded optical activation of DNA recombination in human cells.
– Chemical Communications
(2016)
52,
8529
(doi: 10.1039/c6cc03934k)
Structural and mechanistic insights into the regulation of the fundamental Rho regulator RhoGDIα by lysine acetylation
– The Journal of biological chemistry
(2015)
291,
5484
(doi: 10.1074/jbc.M115.707091)
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