Professor of Chemistry & Chemical Biology
Publications
Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis.
Journal of the American Chemical Society
(2017)
139
8074
(doi: 10.1021/jacs.7b02618)
Biosynthesis and genetic encoding of phosphothreonine through parallel selection and deep sequencing.
Nature Methods
(2017)
14
729
(doi: 10.1038/nmeth.4302)
Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst.
Chemical Science
(2017)
8
3871
(doi: 10.1039/c6sc05313k)
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET
Scientific reports
(2017)
7
39841
(doi: 10.1038/srep39841)
Mitotic phosphorylation of Hsp72 uncouples ATP binding from substrate release and clusters amplified centrosomes in cancer cells.
MOLECULAR BIOLOGY OF THE CELL
(2017)
28
Defining synonymous codon compression schemes by genome recoding.
Nature
(2016)
539
59
(doi: 10.1038/nature20124)
Genetic code expansion in the mouse brain
Nature Chemical Biology
(2016)
12
776
(doi: 10.1038/nchembio.2160)
Tagging and Enriching Proteins Enables Cell-Specific Proteomics
Cell chemical biology
(2016)
23
805
Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity
Cell Reports
(2016)
16
1180
(doi: 10.1016/j.celrep.2016.06.064)
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.
J Am Chem Soc
(2016)
138
718
(doi: 10.1021/jacs.5b07627)
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