Professor of Chemistry & Chemical Biology

Publications

Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis.
JA Gramespacher, AJ Stevens, DP Nguyen, JW Chin, TW Muir
Journal of the American Chemical Society
(2017)
139
Biosynthesis and genetic encoding of phosphothreonine through parallel selection and deep sequencing.
MS Zhang, SF Brunner, N Huguenin-Dezot, AD Liang, WH Schmied, DT Rogerson, JW Chin
Nature Methods
(2017)
14
Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst.
TT-L Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring
Chemical Science
(2017)
8
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET
L Perdios, AR Lowe, G Saladino, TD Bunney, N Thiyagarajan, Y Alexandrov, C Dunsby, PMW French, JW Chin, FL Gervasio, EW Tate, M Katan
Scientific reports
(2017)
7
Mitotic phosphorylation of Hsp72 uncouples ATP binding from substrate release and clusters amplified centrosomes in cancer cells.
M Mukherjee, J Sampson, S Sabir, L O'Regan, MW Richards, N Huguenin-Dezot, MJ Dyer, JW Chin, A Zhuravleva, AM Fry, R Bayliss
MOLECULAR BIOLOGY OF THE CELL
(2017)
28
Defining synonymous codon compression schemes by genome recoding.
K Wang, J Fredens, SF Brunner, SH Kim, T Chia, JW Chin
Nature
(2016)
539
Genetic code expansion in the mouse brain
RJ Ernst, TP Krogager, ES Maywood, R Zanchi, V Beránek, TS Elliott, NP Barry, MH Hastings, JW Chin
Nature Chemical Biology
(2016)
12
Tagging and Enriching Proteins Enables Cell-Specific Proteomics
TS Elliott, A Bianco, FM Townsley, SD Fried, JW Chin
Cell chemical biology
(2016)
23
Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity
N Huguenin-Dezot, V De Cesare, J Peltier, A Knebel, YA Kristaryianto, DT Rogerson, Y Kulathu, M Trost, JW Chin
Cell Reports
(2016)
16
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.
OS Walker, SJ Elsässer, M Mahesh, M Bachman, S Balasubramanian, JW Chin
J Am Chem Soc
(2016)
138

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