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Yusuf Hamied Department of Chemistry

 

Professor of Chemistry & Chemical Biology

Publications

Expanding and reprogramming the genetic code.
JW Chin
– Nature
(2017)
550,
53
Correction: Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling
WD Lambert, SL Scinto, O Dmitrenko, SJ Boyd, R Magboo, RA Mehl, JW Chin, JM Fox, S Wallace
– Org Biomol Chem
(2017)
15,
7476
Computationally guided discovery of a reactive, hydrophilic: Trans -5-oxocene dienophile for bioorthogonal labeling
WD Lambert, SL Scinto, O Dmitrenko, SJ Boyd, R Magboo, RA Mehl, JW Chin, JM Fox, S Wallace
– Organic and Biomolecular Chemistry
(2017)
15,
6640
Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis
JA Gramespacher, AJ Stevens, DP Nguyen, JW Chin, TW Muir
– Journal of the American Chemical Society
(2017)
139,
8074
Biosynthesis and genetic encoding of phosphothreonine through parallel selection and deep sequencing
MS Zhang, SF Brunner, N Huguenin-Dezot, AD Liang, WH Schmied, DT Rogerson, JW Chin
– Nature Methods
(2017)
14,
729
Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst.
TT-L Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring
– Chem Sci
(2017)
8,
3871
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.
L Perdios, AR Lowe, G Saladino, TD Bunney, N Thiyagarajan, Y Alexandrov, C Dunsby, PMW French, JW Chin, FL Gervasio, EW Tate, M Katan
– Scientific Reports
(2017)
7,
39841
Mitotic phosphorylation of Hsp72 uncouples ATP binding from substrate release and clusters amplified centrosomes in cancer cells.
M Mukherjee, J Sampson, S Sabir, L O'Regan, MW Richards, N Huguenin-Dezot, MJ Dyer, JW Chin, A Zhuravleva, AM Fry, R Bayliss
– MOLECULAR BIOLOGY OF THE CELL
(2017)
28,
Defining synonymous codon compression schemes by genome recoding.
K Wang, J Fredens, SF Brunner, SH Kim, T Chia, JW Chin
– Nature
(2016)
539,
59
Genetic code expansion in the mouse brain.
RJ Ernst, TP Krogager, ES Maywood, R Zanchi, V Beránek, TS Elliott, NP Barry, MH Hastings, JW Chin
– Nature chemical biology
(2016)
12,
776
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Research Group

Research Interest Group

Email address

chin@mrc-lmb.cam.ac.uk