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Yusuf Hamied Department of Chemistry

 

Professor of Chemistry & Chemical Biology

Publications

Rapid and Efficient Generation of Stable Antibody–Drug Conjugates via an Encoded Cyclopropene and an Inverse‐Electron‐Demand Diels–Alder Reaction
B Oller-Salvia, G Kym, JW Chin
– Angew Chem Int Ed Engl
(2018)
57,
2831
Detecting RNA base methylations in single cells by in situ hybridization.
RT Ranasinghe, MR Challand, KA Ganzinger, BW Lewis, C Softley, WH Schmied, MH Horrocks, N Shivji, JW Chin, J Spencer, D Klenerman
– Nat Commun
(2018)
9,
655
Labeling and identifying cell-specific proteomes in the mouse brain
TP Krogager, RJ Ernst, TS Elliott, L Calo, V Beránek, E Ciabatti, MG Spillantini, M Tripodi, MH Hastings, JW Chin
– Nat Biotechnol
(2018)
36,
156
Toward an orthogonal central dogma
CC Liu, MC Jewett, JW Chin, CA Voigt
– Nature Chemical Biology
(2018)
14,
103
Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells.
A Liaunardy-Jopeace, BL Murton, M Mahesh, JW Chin, JR James
– Nat Struct Mol Biol
(2017)
24,
1155
Expanding and reprogramming the genetic code
JW Chin
– Nature
(2017)
550,
53
Correction: Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling
WD Lambert, SL Scinto, O Dmitrenko, SJ Boyd, R Magboo, RA Mehl, JW Chin, JM Fox, S Wallace
– Org Biomol Chem
(2017)
15,
7476
Computationally guided discovery of a reactive, hydrophilic trans -5-oxocene dienophile for bioorthogonal labeling
WD Lambert, SL Scinto, O Dmitrenko, SJ Boyd, R Magboo, RA Mehl, JW Chin, JM Fox, S Wallace
– Organic and Biomolecular Chemistry
(2017)
15,
6640
Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis
JA Gramespacher, AJ Stevens, DP Nguyen, JW Chin, TW Muir
– Journal of the American Chemical Society
(2017)
139,
8074
Biosynthesis and genetic encoding of phosphothreonine through parallel setection and deep sequencing
MS Zhang, SF Brunner, N Huguenin-Dezot, AD Liang, WH Schmied, DT Rogerson, JW Chin
– Nat Methods
(2017)
14,
729
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Research Group

Research Interest Group

Email address

chin@mrc-lmb.cam.ac.uk