Professor Jason Chin FMedSci FRS

Professor of Chemistry & Chemical Biology

Publications

Efficient Phage Display with Multiple Distinct Non-Canonical Amino Acids Using Orthogonal Ribosome-Mediated Genetic Code Expansion

B Oller-Salvia, JW Chin

Angewandte Chemie International Edition

(2019)

10844

(doi: 10.1002/anie.201902658)

Total synthesis of Escherichia coli with a recoded genome.

J Fredens, K Wang, D de la Torre, LFH Funke, WE Robertson, Y Christova, T Chia, WH Schmied, DL Dunkelmann, V Beránek, C Uttamapinant, AG Llamazares, TS Elliott, JW Chin

Nature

(2019)

569

514

(doi: 10.1038/s41586-019-1192-5)

Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid

N Huguenin-Dezot, DA Alonzo, GW Heberlig, M Mahesh, DP Nguyen, MH Dornan, CN Boddy, TM Schmeing, JW Chin

Nature

(2018)

565

112

(doi: 10.1038/s41586-018-0781-z)

Controlling orthogonal ribosome subunit interactions enables evolution of new function.

WH Schmied, Z Tnimov, C Uttamapinant, CD Rae, SD Fried, JW Chin

Nature

(2018)

564

444

(doi: 10.1038/s41586-018-0773-z)

Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice

ES Maywood, TS Elliott, AP Patton, TP Krogager, JE Chesham, RJ Ernst, V Beránek, M Brancaccio, JW Chin, MH Hastings

Proceedings of the National Academy of Sciences

(2018)

115

e12388

(doi: 10.1073/pnas.1811438115)

Correction to “Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins”

C Uttamapinant, JD Howe, K Lang, V Beránek, L Davis, M Mahesh, NP Barry, JW Chin

Journal of the American Chemical Society

(2018)

140

13986

(doi: 10.1021/jacs.8b10479)

An Evolved Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase/tRNA Pair Is Highly Active and Orthogonal in Mammalian Cells.

V Beránek, JCW Willis, JW Chin

Biochemistry

(2018)

387

(doi: 10.1021/acs.biochem.8b00808)

A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation.

M Baumdick, M Gelléri, C Uttamapinant, V Beránek, JW Chin, PIH Bastiaens

Nature communications

(2018)

3847

(doi: 10.1038/s41467-018-06299-7)

Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release

M Mukherjee, S Sabir, L O'Regan, J Sampson, MW Richards, N Huguenin-Dezot, JR Ault, JW Chin, A Zhuravleva, AM Fry, R Bayliss

Science Signaling

(2018)

eaao2464

(doi: 10.1126/scisignal.aao2464)

Genetically Encoded Protein Phosphorylation in Mammalian Cells.

V Beránek, CD Reinkemeier, MS Zhang, AD Liang, G Kym, JW Chin

Cell Chemical Biology

(2018)

1067

(doi: 10.1016/j.chembiol.2018.05.013)

Professor Jason Chin FMedSci FRS

Professor of Chemistry & Chemical Biology

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