Professor of Chemistry & Chemical Biology
Publications
Total synthesis of Escherichia coli with a recoded genome
Nature
(2019)
569
514
(doi: 10.1038/s41586-019-1192-5)
Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature
(2018)
565
112
(doi: 10.1038/s41586-018-0781-z)
Controlling orthogonal ribosome subunit interactions enables evolution of new function
Nature
(2018)
564
444
(doi: 10.1038/s41586-018-0773-z)
Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice
Proc Natl Acad Sci U S A
(2018)
115
E12388
(doi: 10.1073/pnas.1811438115)
Correction to "Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins".
J Am Chem Soc
(2018)
140
13986
(doi: 10.1021/jacs.8b10479)
An Evolved Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase/tRNA Pair Is Highly Active and Orthogonal in Mammalian Cells.
Biochemistry
(2018)
58
387
(doi: 10.1021/acs.biochem.8b00808)
A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation.
Nature Communications
(2018)
9
3847
(doi: 10.1038/s41467-018-06299-7)
Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release.
Sci Signal
(2018)
11
eaao2464
(doi: 10.1126/scisignal.aao2464)
Genetically Encoded Protein Phosphorylation in Mammalian Cells.
Cell chemical biology
(2018)
25
1067
Pyrophosphorylation via selective phosphoprotein derivatization.
Chem Sci
(2018)
9
5929
(doi: 10.1039/c8sc01233d)
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