Professor of Chemistry & Chemical Biology
Publications
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms
– Nature
(2020)
579,
603
(doi: 10.1038/s41586-020-2059-5)
Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly.
– Science
(2019)
365,
922
(doi: 10.1126/science.aay0737)
Efficient Phage Display with Multiple Distinct Non‐Canonical Amino Acids Using Orthogonal Ribosome‐Mediated Genetic Code Expansion
– Angewandte Chemie - International Edition
(2019)
58,
10844
(doi: 10.1002/anie.201902658)
Total synthesis of Escherichia coli with a recoded genome
– Nature
(2019)
569,
514
(doi: 10.1038/s41586-019-1192-5)
Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
– Nature
(2018)
565,
112
(doi: 10.1038/s41586-018-0781-z)
Controlling orthogonal ribosome subunit interactions enables evolution of new function
– Nature
(2018)
564,
444
(doi: 10.1038/s41586-018-0773-z)
Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice.
– Proc Natl Acad Sci U S A
(2018)
115,
e12388
(doi: 10.1073/pnas.1811438115)
Correction to: Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins (Journal of the American Chemical Society (2015): 137: (4602-4605): DOI: 10.1021/ja512838z)
– Journal of the American Chemical Society
(2018)
140,
13986
(doi: 10.1021/jacs.8b10479)
An Evolved Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase/tRNA Pair Is Highly Active and Orthogonal in Mammalian Cells
– Biochemistry
(2018)
58,
387
(doi: 10.1021/acs.biochem.8b00808)
A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation
– Nat Commun
(2018)
9,
3847
(doi: 10.1038/s41467-018-06299-7)
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