Yusuf Hamied Department of Chemistry

Professor Jason Chin FMedSci FRS

Professor of Chemistry & Chemical Biology

Publications

Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS
WE Robertson, LFH Funke, D de la Torre, J Fredens, K Wang, JW Chin
Nature protocols
(2021)
16
(doi: 10.1038/s41596-020-00464-3)
Selective CRAF Inhibition Elicits Transactivation.
CW Morgan, IL Dale, AP Thomas, J Hunt, JW Chin
Journal of the American Chemical Society
(2021)
143
(doi: 10.1021/jacs.0c11958)
High-efficacy subcellular micropatterning of proteins using fibrinogen anchors.
JL Watson, S Aich, B Oller-Salvia, AA Drabek, SC Blacklow, J Chin, E Derivery
The Journal of cell biology
(2021)
220
(doi: 10.1083/jcb.202009063)
Reprogramming the genetic code
D de la Torre, JW Chin
Nature Reviews Genetics
(2020)
21
(doi: 10.1038/s41576-020-00307-7)
Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids
DL Dunkelmann, JCW Willis, AT Beattie, JW Chin
Nat Chem
(2020)
12
(doi: 10.1038/s41557-020-0472-x)
Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase–tRNA pairs
D Cervettini, S Tang, SD Fried, JCW Willis, LFH Funke, LJ Colwell, JW Chin
Nature biotechnology
(2020)
38
(doi: 10.1038/s41587-020-0479-2)
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms
MR Hodskinson, A Bolner, K Sato, AN Kamimae-Lanning, K Rooijers, M Witte, M Mahesh, J Silhan, M Petek, DM Williams, J Kind, JW Chin, KJ Patel, P Knipscheer
NATURE
(2020)
579
(doi: 10.1038/s41586-020-2059-5)
Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly.
K Wang, D de la Torre, WE Robertson, JW Chin
Science
(2019)
365
(doi: 10.1126/science.aay0737)
Efficient Phage Display with Multiple Distinct Non‐Canonical Amino Acids Using Orthogonal Ribosome‐Mediated Genetic Code Expansion
B Oller-Salvia, JW Chin
Angewandte Chemie (International ed. in English)
(2019)
58
(doi: 10.1002/anie.201902658)
Total synthesis of Escherichia coli with a recoded genome.
J Fredens, K Wang, D de la Torre, LFH Funke, WE Robertson, Y Christova, T Chia, WH Schmied, DL Dunkelmann, V Beránek, C Uttamapinant, AG Llamazares, TS Elliott, JW Chin
Nature
(2019)
569
(doi: 10.1038/s41586-019-1192-5)

Research Group

Research Interest Group

Email address

chin@mrc-lmb.cam.ac.uk

College

Trinity College
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge