Professor Jason Chin FMedSci FRS

Professor of Chemistry & Chemical Biology

Publications

Reprogramming the genetic code.

D de la Torre, JW Chin

– Nature reviews. Genetics

(2020)

21,

169

(doi: 10.1038/s41576-020-00307-7)

Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids

DL Dunkelmann, JCW Willis, AT Beattie, JW Chin

– Nature chemistry

(2020)

12,

535

(doi: 10.1038/s41557-020-0472-x)

Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs.

D Cervettini, S Tang, SD Fried, JCW Willis, LFH Funke, LJ Colwell, JW Chin

– Nature Biotechnology

(2020)

38,

989

(doi: 10.1038/s41587-020-0479-2)

Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

MR Hodskinson, A Bolner, K Sato, AN Kamimae-Lanning, K Rooijers, M Witte, M Mahesh, J Silhan, M Petek, DM Williams, J Kind, JW Chin, KJ Patel, P Knipscheer

– Nature

(2020)

579,

603

(doi: 10.1038/s41586-020-2059-5)

Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly

K Wang, D de la Torre, WE Robertson, JW Chin

– Science (New York, N.Y.)

(2019)

365,

922

(doi: 10.1126/science.aay0737)

Efficient Phage Display with Multiple Distinct Non-Canonical Amino Acids Using Orthogonal Ribosome-Mediated Genetic Code Expansion.

B Oller-Salvia, JW Chin

– Angewandte Chemie (International ed. in English)

(2019)

58,

10844

(doi: 10.1002/anie.201902658)

Total synthesis of Escherichia coli with a recoded genome.

J Fredens, K Wang, D de la Torre, LFH Funke, WE Robertson, Y Christova, T Chia, WH Schmied, DL Dunkelmann, V Beránek, C Uttamapinant, AG Llamazares, TS Elliott, JW Chin

– Nature

(2019)

569,

514

(doi: 10.1038/s41586-019-1192-5)