Professor of Chemistry & Chemical Biology
Publications
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design.
– Nat Chem
(2021)
13,
1110
(doi: 10.1038/s41557-021-00764-5)
Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase.
– eLife
(2021)
10,
e67075
(doi: 10.7554/eLife.67075)
Sense codon reassignment enables viral resistance and encoded polymer synthesis.
– Science (New York, N.Y.)
(2021)
372,
1057
(doi: 10.1126/science.abg3029)
Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS
– Nature Protocols
(2021)
16,
2345
(doi: 10.1038/s41596-020-00464-3)
Selective CRAF Inhibition Elicits Transactivation
– J Am Chem Soc
(2021)
143,
4600
(doi: 10.1021/jacs.0c11958)
High-efficacy subcellular micropatterning of proteins using fibrinogen anchors
– J Cell Biol
(2021)
220,
e202009063
(doi: 10.1083/jcb.202009063)
Reprogramming the genetic code
– Nature Reviews Genetics
(2020)
22,
169
(doi: 10.1038/s41576-020-00307-7)
Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids
– Nature Chemistry
(2020)
12,
535
(doi: 10.1038/s41557-020-0472-x)
Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs
– Nature biotechnology
(2020)
38,
989
(doi: 10.1038/s41587-020-0479-2)
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms
– Nature
(2020)
579,
603
(doi: 10.1038/s41586-020-2059-5)
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