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Yusuf Hamied Department of Chemistry

 

Professor of Chemistry & Chemical Biology

Publications

Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.
F Bürmann, LFH Funke, JW Chin, J Löwe
– Mol Cell
(2021)
81,
4891
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design
DL Dunkelmann, SB Oehm, AT Beattie, JW Chin
– Nature Chemistry
(2021)
13,
1110
Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase.
L Davis, I Radman, A Goutou, A Tynan, K Baxter, Z Xi, JM O'Shea, JW Chin, S Greiss
– eLife
(2021)
10,
e67075
Sense codon reassignment enables viral resistance and encoded polymer synthesis
WE Robertson, LFH Funke, D de la Torre, J Fredens, TS Elliott, M Spinck, Y Christova, D Cervettini, FL Böge, KC Liu, S Buse, S Maslen, GPC Salmond, JW Chin
– Science (New York, N.Y.)
(2021)
372,
1057
Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS
WE Robertson, LFH Funke, D de la Torre, J Fredens, K Wang, JW Chin
– Nature Protocols
(2021)
16,
2345
Selective CRAF Inhibition Elicits Transactivation.
CW Morgan, IL Dale, AP Thomas, J Hunt, JW Chin
– Journal of the American Chemical Society
(2021)
143,
4600
High-efficacy subcellular micropatterning of proteins using fibrinogen anchors
JL Watson, S Aich, B Oller-Salvia, AA Drabek, SC Blacklow, J Chin, E Derivery
– J Cell Biol
(2021)
220,
e202009063
Reprogramming the genetic code.
D de la Torre, JW Chin
– Nature reviews. Genetics
(2020)
22,
169
Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids
DL Dunkelmann, JCW Willis, AT Beattie, JW Chin
– Nature Chemistry
(2020)
12,
535
Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs
D Cervettini, S Tang, SD Fried, JCW Willis, LFH Funke, LJ Colwell, JW Chin
– Nat Biotechnol
(2020)
38,
989
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Research Group

Research Interest Group

Email address

chin@mrc-lmb.cam.ac.uk