Professor of Chemistry & Chemical Biology
Publications
RBBP6 activates the pre-mRNA 3' end processing machinery in humans.
– Genes & Development
(2022)
36,
210
(doi: 10.1101/gad.349223.121)
Mechanism-based traps enable protease and hydrolase substrate discovery.
– Nature
(2022)
602,
701
(doi: 10.1038/s41586-022-04414-9)
Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons.
– Proc Natl Acad Sci U S A
(2022)
119,
e2113845119
(doi: 10.1073/pnas.2113845119)
Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.
– Molecular cell
(2021)
81,
4891
(doi: 10.1016/j.molcel.2021.10.011)
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design
– Nat Chem
(2021)
13,
1110
(doi: 10.1038/s41557-021-00764-5)
Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase
– eLife
(2021)
10,
e67075
(doi: 10.7554/elife.67075)
Sense codon reassignment enables viral resistance and encoded polymer synthesis
– Science
(2021)
372,
1057
(doi: 10.1126/science.abg3029)
Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS
– Nature Protocols
(2021)
16,
2345
(doi: 10.1038/s41596-020-00464-3)
Selective CRAF Inhibition Elicits Transactivation.
– J Am Chem Soc
(2021)
143,
4600
(doi: 10.1021/jacs.0c11958)
High-efficacy subcellular micropatterning of proteins using fibrinogen anchors.
– J Cell Biol
(2021)
220,
e202009063
(doi: 10.1083/jcb.202009063)
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