Professor of Chemistry & Chemical Biology

Publications

Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne.
T Machida, K Lang, L Xue, JW Chin, N Winssinger
Bioconjug Chem
(2015)
26
Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization
J Madrzak, M Fiedler, CM Johnson, R Ewan, A Knebel, M Bienz, JW Chin
Nature communications
(2015)
6
Genetic code expansion enables live-cell and super-resolution imaging of site-specifically labeled cellular proteins.
C Uttamapinant, JD Howe, K Lang, V Beránek, L Davis, M Mahesh, NP Barry, JW Chin
Journal of the American Chemical Society
(2015)
137
Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers
JS Bett, MS Ritorto, R Ewan, EG Jaffray, S Virdee, JW Chin, A Knebel, T Kurz, M Trost, MH Tatham, RT Hay
Biochemical Journal
(2015)
466
Genetic encoding of unnatural amino acids for labeling proteins.
JWK Chin, K Lang, L Davis
Methods in molecular biology
(2014)
Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.
AJ Price, DA Jacques, WA McEwan, AJ Fletcher, S Essig, JW Chin, UD Halambage, C Aiken, LC James
PLOS Pathogens
(2014)
10
Efficient multisite unnatural amino acid incorporation in mammalian cells via optimized pyrrolysyl tRNA synthetase/tRNA expression and engineered eRF1.
WH Schmied, SJ Elsässer, C Uttamapinant, JW Chin
J Am Chem Soc
(2014)
136
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation.
J Luo, R Uprety, Y Naro, C Chou, DP Nguyen, JW Chin, A Deiters
J Am Chem Soc
(2014)
136
Genetic code expansion and bioorthogonal labelling enables cell specific proteomics in an animal.
TS Elliott, A Bianco, JW Chin
Current opinion in chemical biology
(2014)
21
HIV-1 capsid binds host cofactors to mediate nuclear import
A Price, D Jacques, S Essig, T Elliott, U Halambage, J Chin, C Aiken, L James
Acta Crystallographica Section A Foundations and Advances
(2014)
70

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