Professor of Chemistry & Chemical Biology
Publications
Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne.
Bioconjug Chem
(2015)
26
802
Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization
Nature communications
(2015)
6
6718
(doi: 10.1038/ncomms7718)
Genetic code expansion enables live-cell and super-resolution imaging of site-specifically labeled cellular proteins.
Journal of the American Chemical Society
(2015)
137
4602
(doi: 10.1021/ja512838z)
Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers
Biochemical Journal
(2015)
466
489
(doi: 10.1042/bj20141349)
Genetic encoding of unnatural amino acids for labeling proteins.
Methods in molecular biology
(2014)
(doi: 10.1007/978)
Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.
PLOS Pathogens
(2014)
10
e1004459
(doi: 10.1371/journal.ppat.1004459)
Efficient multisite unnatural amino acid incorporation in mammalian cells via optimized pyrrolysyl tRNA synthetase/tRNA expression and engineered eRF1.
J Am Chem Soc
(2014)
136
15577
(doi: 10.1021/ja5069728)
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation.
J Am Chem Soc
(2014)
136
15551
(doi: 10.1021/ja5055862)
Genetic code expansion and bioorthogonal labelling enables cell specific proteomics in an animal.
Current opinion in chemical biology
(2014)
21
154
(doi: 10.1016/j.cbpa.2014.07.001)
HIV-1 capsid binds host cofactors to mediate nuclear import
Acta Crystallographica Section A Foundations and Advances
(2014)
70
c120
(doi: 10.1107/S2053273314098799)
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