Professor of Chemistry & Chemical Biology
Publications
Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne.
Bioconjug Chem
(2015)
26
802
Genetic code expansion enables live-cell and super-resolution imaging of site-specifically labeled cellular proteins.
J Am Chem Soc
(2015)
137
4602
(doi: 10.1021/ja512838z)
Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers.
Biochem J
(2015)
466
489
(doi: 10.1042/BJ20141349)
Genetic encoding of unnatural amino acids for labeling proteins.
Methods in molecular biology
(2014)
(doi: 10.1007/978)
Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.
Plos Pathogens
(2014)
10
e1004459
(doi: 10.1371/journal.ppat.1004459)
Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1
J Am Chem Soc
(2014)
136
15577
(doi: 10.1021/ja5069728)
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation.
J Am Chem Soc
(2014)
136
15551
(doi: 10.1021/ja5055862)
Genetic code expansion and bioorthogonal labelling enables cell specific proteomics in an animal
Current Opinion in Chemical Biology
(2014)
21
154
(doi: 10.1016/j.cbpa.2014.07.001)
HIV-1 capsid binds host cofactors to mediate nuclear import
Acta Crystallographica Section A Foundations and Advances
(2014)
70
C120
(doi: 10.1107/s2053273314098799)
Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins
Journal of the American Chemical Society
(2014)
136
7785
(doi: 10.1021/ja4129789)
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