Yusuf Hamied Department of Chemistry

Professor David Spring

Professor of Chemistry & Chemical Biology / EPSRC Established Career Research Fellow

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Copper catalyzed oxidation of organozinc halides.
X Su, DJ Fox, DT Blackwell, K Tanaka, DR Spring
Chem Commun (Camb)
(2006)
(doi: 10.1039/b610218b)
Variations on a Theme: Diverse N-Acyl Homoserine Lactone-Mediated Quorum Sensing Mechanisms in Gram-Negative Bacteria
D Smith, J-H Wang, JE Swatton, P Davenport, B Price, H Mikkelsen, H Stickland, K Nishikawa, N Gardiol, DR Spring, M Welch
Science Progress
(2006)
89
(doi: 10.3184/003685006783238335)
Skeletal diversity construction via a branching synthetic strategy
EE Wyatt, S Fergus, W Galloway, A Bender, DJ Fox, AT Plowright, AS Jessiman, M Welch, DR Spring
Chem Commun (Camb)
(2006)
(doi: 10.1039/b607710b)
Metabolic and regulatory engineering of Serratia marcescens: mimicking phage-mediated horizontal acquisition of antibiotic biosynthesis and quorum sensing capacities
SJ Coulthurst, NR Williamson, AKP Harris, DR Spring, GPC Salmond
Microbiology
(2006)
152
(doi: 10.1099/mic.0.28803-0)
Immunomodulatory effects of Pseudomonas aeruginosa quorum sensing small molecule probes on mammalian macrophages.
GL Thomas, CM Bohner, HE Williams, CM Walsh, M Ladlow, M Welch, CE Bryant, DR Spring
Molecular Biosystems
(2006)
2
(doi: 10.1039/b517248a)
Diversity oriented synthesis: A challenge for synthetic chemists
A Bender, S Fergus, WRJD Galloway, FG Glansdorp, DM Marsden, RL Nicholson, RJ Spandl, GL Thomas, EE Wyatt, RC Glen, DR Spring
Ernst Schering Research Foundation Workshop
(2006)
58
(doi: 10.1007/978-3-540-37635-4_4)
Synthesis and utilization of functionalized polystyrene resins
GL Thomas, C Böhner, M Ladlow, DR Spring
Tetrahedron
(2005)
61
(doi: 10.1016/j.tet.2005.07.118)
The oxidation of organocuprates--an offbeat strategy for synthesis.
DS Surry, DR Spring
Chemical Society Reviews
(2005)
35
(doi: 10.1039/b508391p)
Structure–activity relationships of Erwinia carotovora quorum sensing signaling molecules
M Welch, JM Dutton, FG Glansdorp, GL Thomas, DS Smith, SJ Coulthurst, AML Barnard, GPC Salmond, DR Spring
Bioorganic & Medicinal Chemistry Letters
(2005)
15
(doi: 10.1016/j.bmcl.2005.06.066)
Cell-cell communication in gram-negative bacteria
M Welch, H Mikkelsen, JE Swatton, D Smith, GL Thomas, FG Glansdorp, DR Spring
Mol Biosyst
(2005)
1
(doi: 10.1039/b505796p)

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address

spring@ch.cam.ac.uk

College

Trinity College
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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