Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Fluorous tagged small molecule microarrays (Chemical Communications (2007) (3906) DOI: 10.1039/b712906h)
RL Nicholson, ML Ladlow, DR Spring
Chemical Communications
(2007)
Enriching chemical space with diversity-oriented synthesis
GL Thomas, EE Wyatt, DR Spring
Curr Opin Drug Discov Devel
(2006)
9
ORGN 410-Adventures in diversity-oriented synthesis
DR Spring
ABSTR PAP AM CHEM S
(2006)
232
Copper catalyzed oxidation of organozinc halides
X Su, DJ Fox, DT Blackwell, K Tanaka, DR Spring
Chem Commun (Camb)
(2006)
Skeletal diversity construction via a branching synthetic strategy.
EE Wyatt, S Fergus, W Galloway, A Bender, DJ Fox, AT Plowright, AS Jessiman, M Welch, DR Spring
Chem Commun (Camb)
(2006)
Metabolic and regulatory engineering of Serratia marcescens: mimicking phage-mediated horizontal acquisition of antibiotic biosynthesis and quorum-sensing capacities
SJ Coulthurst, NR Williamson, AKP Harris, DR Spring, GPC Salmond
Microbiology
(2006)
152
Immunomodulatory effects of Pseudomonas aeruginosa quorum sensing small molecule probes on mammalian macrophages
GL Thomas, CM Bohner, HE Williams, CM Walsh, M Ladlow, M Welch, CE Bryant, DR Spring
Molecular BioSystems
(2006)
2
Diversity oriented synthesis: a challenge for synthetic chemists.
A Bender, S Fergus, WRJD Galloway, FG Glansdorp, DM Marsden, RL Nicholson, RJ Spandl, GL Thomas, EE Wyatt, RC Glen, DR Spring
Ernst Schering Res Found Workshop
(2006)
58
Synthesis and utilization of functionalized polystyrene resins
GL Thomas, C Böhner, M Ladlow, DR Spring
Tetrahedron
(2005)
61
The oxidation of organocuprates—an offbeat strategy for synthesis
DS Surry, DR Spring
Chem Soc Rev
(2005)
35

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address