Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation
Z Walsh, E-R Janeček, JT Hodgkinson, J Sedlmair, A Koutsioubas, DR Spring, M Welch, CJ Hirschmugl, C Toprakcioglu, JR Nitschke, M Jones, OA Scherman
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
Linear Aliphatic Dialkynes as Alternative Linkers for Double-Click Stapling of p53-Derived Peptides
YH Lau, P de Andrade, GJ McKenzie, AR Venkitaraman, DR Spring
ChemBioChem
(2014)
15
Diversity-oriented synthesis of drug-like macrocyclic scaffolds using an orthogonal organo- and metal catalysis strategy
A Grossmann, S Bartlett, M Janecek, JT Hodgkinson, DR Spring
Angew Chem Int Ed Engl
(2014)
53
Synthesis of a novel polycyclic ring scaffold with antimitotic properties
E Alza, L Laraia, BM Ibbeson, S Collins, WRJD Galloway, JE Stokes, AR Venkitaraman, DR Spring
Chem Sci
(2014)
6
Peptide stapling techniques based on different macrocyclisation chemistries
YH Lau, P de Andrade, Y Wu, DR Spring
Chemical Society Reviews
(2014)
44
Concise synthesis of substituted quinolizin-4-ones by ring-closing metathesis
TA Alanine, WRJD Galloway, TM McGuire, DR Spring
European Journal of Organic Chemistry
(2014)
2014
Diversity‐Oriented Synthesis: Developing New Chemical Tools to Probe and Modulate Biological Systems
WRJD Galloway, D Wilcke, F Nie, K Hadje‐Georgiou, L Laraia, DR Spring
(2014)
9783527336111
Unusual Z-selectivity in the Takai olefination: Evidence for a competing chelation reaction mechanism
CE Hagerman, SM Geddis, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Diversity-oriented synthesis on partially saturated heteroaromatic scaffolds
DG Twigg, T Nowak, L Spadola, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Hydrosilylation as a novel bioorthogonal reaction
MK Gupta, EC Frye, TT-L Kwan, F Zhang, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address