Professor of Chemistry & Chemical Biology / EPSRC Established Career Research Fellow

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Aqeuous hydrosilylation: Application to site-selective protein modification
TT-L Kwan, EC Frye, MK Gupta, M Welch, JW Chin, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Chemical probes for studying cell-to-cell communication in bacteria
YR Baker, JT Hodgkinson, M Welch, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Unusual Z-selectivity in the Takai olefination: Evidence for a competing chelation reaction mechanism
CE Hagerman, SM Geddis, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Small molecule modulation of quorum sensing pathways
DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
247
Functionalised staple linkages for modulating the cellular activity of stapled peptides
YH Lau, P de Andrade, S-T Quah, M Rossmann, L Laraia, N Sköld, TJ Sum, PJE Rowling, TL Joseph, C Verma, M Hyvönen, LS Itzhaki, AR Venkitaraman, CJ Brown, DP Lane, DR Spring
Chem. Sci.
(2014)
5
Development of small-molecule inhibitors of Aurora kinase A: TPX2 protein-protein interaction
M Janecek, P Sharma, M Rossmann, G McKenzie, M Hyvoenen, DR Spring, AR Venkitaraman
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Targeting mitochondria in prostate cancer with the rotenoid group of natural products
DA Russell, DR Spring, DE Neal, LG Fryer
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Hydrosilylation as a novel bioorthogonal reaction
MK Gupta, EC Frye, TT-L Kwan, F Zhang, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Diversity-oriented synthesis of macrocyclic scaffolds based on a quinine core
J Ciardiello, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248
Diversity-oriented synthesis on partially saturated heteroaromatic scaffolds
DG Twigg, T Nowak, L Spadola, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address