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Yusuf Hamied Department of Chemistry

 

Professor David Spring

Professor of Chemistry & Chemical Biology / EPSRC Established Career Research Fellow

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation
Z Walsh, E-R Janeček, JT Hodgkinson, J Sedlmair, A Koutsioubas, DR Spring, M Welch, CJ Hirschmugl, C Toprakcioglu, JR Nitschke, M Jones, OA Scherman
– Proceedings of the National Academy of Sciences
(2014)
111,
17743
(doi: 10.1073/pnas.1406037111)
Linear Aliphatic Dialkynes as Alternative Linkers for Double‐Click Stapling of p53‐Derived Peptides
YH Lau, P de Andrade, GJ McKenzie, AR Venkitaraman, DR Spring
– Chembiochem : a European journal of chemical biology
(2014)
15,
2680
(doi: 10.1002/cbic.201402374)
Diversity-Oriented Synthesis: Developing New Chemical Tools to Probe and Modulate Biological Systems
WRJD Galloway, D Wilcke, F Nie, K Hadje-Georgiou, L Laraia, DR Spring
(2014)
9783527336111,
379
(doi: 10.1002/9783527687503.ch26)
Diversity-Oriented Synthesis of Drug-Like Macrocyclic Scaffolds Using an Orthogonal Organo- and Metal Catalysis Strategy
A Grossmann, S Bartlett, M Janecek, JT Hodgkinson, DR Spring
– Angewandte Chemie International Edition
(2014)
53,
13093
(doi: 10.1002/anie.201406865)
Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck-Suzuki reaction.
E Alza, L Laraia, BM Ibbeson, S Collins, WRJD Galloway, JE Stokes, AR Venkitaraman, DR Spring
– Chemical science
(2014)
6,
390
(doi: 10.1039/c4sc02547d)
Peptide stapling techniques based on different macrocyclisation chemistries
YH Lau, P de Andrade, Y Wu, DR Spring
– Chem Soc Rev
(2014)
44,
91
(doi: 10.1039/c4cs00246f)
Concise synthesis of substituted quinolizin-4-ones by ring-closing metathesis
TA Alanine, WRJD Galloway, TM McGuire, DR Spring
– European Journal of Organic Chemistry
(2014)
2014,
5767
(doi: 10.1002/ejoc.201402648)
Concise Synthesis of Substituted Quinolizin-4-ones by Ring-Closing Metathesis
TA Alanine, WRJD Galloway, TM Mcguire, DR Spring
– European Journal of Organic Chemistry
(2014)
2014,
5767
(doi: 10.1002/ejoc.201402648)
Toxicity of six plant extracts and two pyridone alkaloids from Ricinus communis against the malaria vector Anopheles gambiae
SW Wachira, S Omar, JW Jacob, M Wahome, HT Alborn, DR Spring, DK Masiga, B Torto
– Parasites & vectors
(2014)
7,
312
(doi: 10.1186/1756-3305-7-312)
Arene C-H functionalisation using a removable/modifiable or a traceless directing group strategy
F Zhang, DR Spring
– Chemical Society Reviews
(2014)
43,
6906
(doi: 10.1039/c4cs00137k)
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Research Group

Research Interest Groups

Telephone number

01223 336498

Email address

spring@ch.cam.ac.uk

College

Trinity College

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    About the University

    Research at Cambridge