Yusuf Hamied Department of Chemistry

Professor David Spring

Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Synthesis and biological evaluation of 1,2-disubstituted 4-quinolone analogues of Pseudonocardia sp. natural products
SM Geddis, T Coroama, S Forrest, JT Hodgkinson, M Welch, DR Spring
Beilstein J Org Chem
(2018)
14
(doi: 10.3762/bjoc.14.245)
Recent applications of diversity-oriented synthesis Toward novel, 3-dimensional fragment collections
SL Kidd, TJ Osberger, N Mateu, HF Sore, DR Spring
Frontiers in Chemistry
(2018)
6
(doi: 10.3389/fchem.2018.00460)
Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
PG Flammer, S Dellicour, SG Preston, D Rieger, S Warren, CKW Tan, R Nicholson, R Přichystalová, N Bleicher, J Wahl, NR Faria, OG Pybus, M Pollard, AL Smith
Proceedings of the Royal Society B
(2018)
285
(doi: 10.1098/rspb.2018.0991)
Synthesis of structurally diverse biflavonoids
TJ Sum, TH Sum, WRJD Galloway, DG Twigg, JJ Ciardiello, DR Spring
Tetrahedron
(2018)
74
(doi: 10.1016/j.tet.2018.05.003)
Synthesis of Structurally Diverse N-Substituted Quaternary-Carbon-Containing Small Molecules from α,α-Disubstituted Propargyl Amino Esters
N Mateu, SL Kidd, L Kalash, HF Sore, A Madin, A Bender, DR Spring
Chemistry (Weinheim an der Bergstrasse, Germany)
(2018)
24
(doi: 10.1002/chem.201803143)
Semi-syntheses of the 11-hydroxyrotenoids sumatrol and villosinol
DA Russell, JJ Freudenreich, HL Stewart, AD Bond, HF Sore, DR Spring
Organic & Biomolecular Chemistry
(2018)
16
(doi: 10.1039/c8ob01919c)
Two-component stapling of biologically active and conformationally constrained peptides: past, present and future
J Iegre, JS Gaynord, NS Robertson, HF Sore, M Hyvönen, DR Spring
Advanced Therapeutics
(2018)
1
(doi: 10.1002/adtp.201800052)
Novel non-ATP competitive small molecules targeting the CK2 α/β interface
P Brear, AJP North, J Iegre, K Hadje Georgiou, A Lubin, L Carro, W Green, H Sore, M Hyvonen, D Spring
Bioorg Med Chem
(2018)
26
(doi: 10.1016/j.bmc.2018.05.011)
Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons
E Bilsland, TA Tavella, R Krogh, JE Stokes, A Roberts, J Ajioka, DR Spring, AD Andricopulo, FTM Costa, SG Oliver
BMC biotechnology
(2018)
18
(doi: 10.1186/s12896-018-0428-z)
Studies Towards the Synthesis of the Core of Endiandric Acid H
S Zheng, D Yang, R Zhu, DR Spring
Chemistry of Natural Compounds
(2018)
54
(doi: 10.1007/s10600-018-2326-y)

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address

spring@ch.cam.ac.uk

College

Trinity College
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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