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Welcome to the Department of Chemistry NMR facility

We provide NMR analytical chemistry services to:

  • Research workers within the department
  • Research workers in other University departments
  • External customers (please contact the NMR Service, who will be able to answer your enquiry)

Equipment

  • 13 high field superconducting magnet systems, with associated hardware, enabling a wide variety of experiments at various field strengths 
  • A separate Solid State NMR facility for the group of Professor Clare Grey  (more information available at the Grey Research Group website)

For more information about the individual instruments and their capabilities, go to the NMR Spectrometers page.

Services and supplies

  • A large range of deuterated solvents and NMR tubes.
  • Other chemicals of use in NMR spectroscopy.  
  • Assistance with basic interpretation of results
  • Tips on how to process your spectra to get the best results
  • Help with TopSpin, planning experiments, setting up the spectrometers, modifying pulse programs, automation, DOSY, NUS, Slice Selective NMR, VT, Kinetics, and much more.

TopSpin 4.x is now supplied free by Bruker for academic use.For new members of the department wishing to get a copy of TopSpin for themselves - please see the instructions available below for getting it installed and using it to process your spectra. We recommend that all users of the NMR facilities view their spectra on a computer in order to extract the most information.

Installation guide - https://www.ch.cam.ac.uk/analytical/nmr/files/topspin4-installation2017-12-22.pdf

Processing with TopSpin, written by Duncan - https://www.ch.cam.ac.uk/analytical/nmr/files/topspin-processing-2016-10-31-handouta.pdf

A Spectrometer Comparison Chart correct from January 2019 can be found at the bottom of the drop down Spectrometers menu - please consult this to ascertain your best route for getting your NMR results!

We are generally always busy, with a lot of samples in the in-tray.  You may receive an email with your data enclosed before your spectra have been checked and your sample is returned.  If you have checked your data personally and are happy with the results please inform us, and we will put your NMR sample tube out to be collected.

As a rule we DO NOT print the spectra out because most of our users are happy with the electronic data, and we are trying to cut down on the amount of paper used in the section.  If you have a reason for requiring the spectra to be printed please inform us by email or in person.

Contact us

For more information on what the spectrometers might do for you, please contact one of the NMR Service staff:

Or email all the NMR team at once using nmr@ch.cam.ac.uk

You can find more information about the NMR Service staff members here. If you have questions about any aspect of the NMR service, email, phone or drop by our office in the basement (Room B28).

We have a twitter account - @camnmrservice - https://twitter.com/camnmrservice/  We will use this for status updates, important news and tips.  Any good questions we get through other channels may well end up here as general information for everyone.  We look forward to receiving your tweets!

Current status

The TCI 500 now has a "loan" TCI cryoprobe from Bruker installed. The engineer has also diagnosed and fixed the 2H TX power issue by replacing and recabling an SGU. Notes on the failure are still below and will remain for a few weeks.

The pulse lengths and power handling are different from the previous probe. Therefore please refer to the email that Duncan sent to you on Thursday 8th August. DO NOT use "old" parameter sets or datasets from the archives. YOU MUST start with a new parameter set as created by the NMR team. They are all titled *.tci. The gramicidin-s data which Duncan used to prepare the *.tci parameter sets can be found in the D:/data/<yourgroup>/nmr directory. Drag this into TopSpin on your first log-in and start from there!!! Please ask for help with more complicated experiments, however the service *.tci parameters will have most of the pulses etc needed to get things going again!!

This will enable us to put the instrument back into full service to keep research output at a high level.

Previously:   "The TCI 500 Spectrometer Glenlivet is in limited service. A power supply and fans failed above and behind the SGU boards in the AQR module which prompted overheating warnings. We had spare fans and a power supply in our storeroom and this work was successful in repairing the initial fault. Unfortunately we have a very poor 2H S/N causing TopShim to fail to work correctly. Although the spectrometer does not have TopShim with 2H, any user wishing to manually shim their samples or use TopShim 1H with H2O/D2O capillaries should see the NMR team. A faulty valve leaking in the Cryoplatform has now been replaced, apologies for the week of disruption with that. To top off our misfortune with this fated instrument the tuning on the 1H Channel is unable to reach a fully tuned and matched state. We have replaced the ATM module with the manual tuning accessory and recalibrated the 1H pulse length."

The 700MHz spectrometer Arran is now working in general use with solid and solution probes. Please liaise with the NMR team or Giuliana Fusco in the Dobson Group (gf203@cam.ac.uk) for access to this instrument, or if you think your sample could benefit from being run at this frequency.

All four of our open-access spectrometers are now in use with NMRKiosk. Laphroaig, the 400MHz in B18 is still using the loan QNP probe whilst the SmartProbe is away being repaired. We expect this to continue until mid-August according to the latest repair estimate from Bruker. Please respect the booking rules on all the open-access instruments during this period of slight disruption, and think of which is the best option available for getting your spectroscopy needs met.

All of our other instruments are operational at present, although Cragganmore (Service 400MHz QNP Cryoprobe in B28) is unable to run 19F or 31P spectra until further notice.

Future Developments

We hope to soon rename the 400MHz spectrometer in B13 from Florence to Auchentoshan to standardise the names of all of our spectrometers as Single Malt Scotch Whisky distilleries.

A price review of the open-access spectrometers has taken place. The charges are now:

£1.00 per short experiment (1H, 11B, 19F, 31P, Quick 1H+COSY, 1H with water suppression etc) dropping to £0.50 for 100+ short experiments.

£4.00 per long experiment (13C+DEPT, PCD, Quick WORKS, Overnight 1H, 19F or 31P etc)

£6.00 per very long experiment (FULL WORKS -1H+13C+DEPT+COSY+HSQC+HMBC)

In future we hope to standardise the naming of the experiments so that each spectrometer has identically named options.

Submission forms for samples for the NMR Service (in PDF and Powerpoint formats) for downloading: