Research Fellow

Toby is a Herchel Smith Fellow in the Department of Chemistry establishing new gene encoded supramolecular structures for the development of biocompatible molecular machines that operate in cellulo. 

He obtained his MChem from Durham University in 2019, conducting his final year research project with Prof. Paul McGonigal. In 2023, he completed his DPhil in Inorganic Chemistry at Oxford University under the supervision of Prof. Matthew Langton developing molecular machines for the control of transmembrane ion transport. Toby then moved to Princeton University to take up a position as a Lindemann Trust Fellow in the group of Prof. Jamie Link before securing an Omenn-Darling Fellowship to engineer new-to-nature mechanically interlocked peptides. Recently, he has secured a Herchel Smith Fellowship at the University of Cambridge, to develop gene encoded supramolecular structures. His research interests lie at the interface between stimuli-responsive supramolecular chemistry and biological discovery of mechanically interlocked natural products.

Publications

Tangled Tail of Mechanically Interlocked Peptides.
TG Johnson, AJ Link
J Am Chem Soc
(2026)
148
Biosynthesis, Structure, and Antibiotic Properties of Gelatinamin A, a Triculamin-Like Lasso Peptide
T Svenningsen, A Merrild, F Wang, FD Hansen, TG Johnson, R Iwase, T Viennet, MK Larsen, AJ Link, T Tørring
ChemBioChem
(2026)
27
Repositioning the Leader Peptide in Graspetide Biosynthesis.
TG Johnson, DM Miller, DV Carson, B Choi, AJ Link
Journal of the American Chemical Society
(2026)
148
Biosynthesis, Structure, and Antibiotic Properties of Gelatinamin A, a Triculamin-like Lasso Peptide
T Svenningsen, A Merrild, F Wang, FD Hansen, TG Johnson, R Iwase, T Viennet, MK Larsen, AJ Link, T Tørring
(2025)
Peptide and Protein Cyclization by a Promiscuous Graspetide Synthetase
B Choi, TG Johnson, A Acuña, HE Elashal, AJ Link
ACS Cent Sci
(2025)
11
Probing Thrombosis Initiation with Lasso Peptide Variants as Inhibitors to the von Willebrand Protein–Collagen Interaction
DA Guarracino, DV Carson, TG Johnson, AJ Link
ChemBioChem
(2025)
26
Responsive Anionophores with AND Logic Multi‐Stimuli Activation
M Ahmad, TG Johnson, M Flerin, F Duarte, MJ Langton
Angew Chem Int Ed Engl
(2024)
63
Responsive Anionophores with AND Logic Multi‐Stimuli Activation
M Ahmad, TG Johnson, M Flerin, F Duarte, MJ Langton
Angewandte Chemie
(2024)
136
Coupling Photoresponsive Transmembrane Ion Transport with Transition Metal Catalysis
X Chao, TG Johnson, M-C Temian, A Docker, ALD Wallabregue, A Scott, SJ Conway, MJ Langton
Journal of the American Chemical Society
(2024)
146
Length dependent reversible off-on activation of photo-switchable relay anion transporters.
TG Johnson, A Sadeghi-Kelishadi, MJ Langton
Chem Commun (Camb)
(2024)
60

Research Group

Email address