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Yusuf Hamied Department of Chemistry

 

Publications

Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study.
EL Atkinson, J Iegre, PD Brear, EA Zhabina, M Hyvönen, DR Spring
– Molecules (Basel, Switzerland)
(2021)
26,
1977
Chemical probes targeting the kinase CK2: A journey outside the catalytic box
J Iegre, EL Atkinson, PD Brear, BM Cooper, M Hyvönen, DR Spring
– Org Biomol Chem
(2021)
19,
4380
Peptides as a platform for targeted therapeutics for cancer: Peptide-drug conjugates (PDCs)
BM Cooper, J Iegre, DH O' Donovan, M Ölwegård Halvarsson, DR Spring
– Chem Soc Rev
(2021)
50,
1480
General dual functionalisation of biomacromoleculesviaa cysteine bridging strategy
SJ Walsh, J Iegre, H Seki, JD Bargh, HF Sore, JS Parker, JS Carroll, DR Spring
– Organic & biomolecular chemistry
(2020)
18,
4224
Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides.
J Charoenpattarapreeda, YS Tan, J Iegre, SJ Walsh, E Fowler, RS Eapen, Y Wu, HF Sore, CS Verma, L Itzhaki, DR Spring
– Chemical communications (Cambridge, England)
(2019)
55,
7914
Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction
J Iegre, P Brear, DJ Baker, YS Tan, EL Atkinson, HF Sore, DH O' Donovan, CS Verma, M Hyvönen, DR Spring
– Chemical Science
(2019)
10,
5056
Two-component stapling of biologically active and conformationally constrained peptides: past, present and future
J Iegre, JS Gaynord, NS Robertson, HF Sore, M Hyvönen, DR Spring
– Advanced Therapeutics
(2018)
1,
1800052
Novel non-ATP competitive small molecules targeting the CK2 alpha/beta interface
P Brear, AJP North, J Iegre, K Hadje Georgiou, A Lubin, L Carro, W Green, H Sore, M Hyvonen, D Spring
– Bioorg Med Chem
(2018)
26,
3016
Second-generation CK2 alpha inhibitors targeting the alpha D pocket
J Iegre, P Brear, C De Fusco, M Yoshida, SL Mitchell, M Rossmann, L Carro, HF Sore, M Hyvönen, DR Spring
– Chemical science
(2018)
9,
3041
Stapled peptides as a new technology to investigate protein–protein interactions in human platelets
J Iegre, NS Ahmed, JS Gaynord, Y Wu, KM Herlihy, YS Tan, ME Lopes-Pires, R Jha, YH Lau, HF Sore, C Verma, DH O' Donovan, N Pugh, DR Spring
– Chem Sci
(2018)
9,
4638
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Research Group

Email address

ji243@cam.ac.uk