
Professor of Chemistry & Chemical Biology
Publications
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles
– Nat Chem
(2022)
15,
61
(DOI: 10.1038/s41557-022-01082-0)
Refactored genetic codes enable bidirectional genetic isolation
– Science
(2022)
378,
eadd8943
(DOI: 10.1126/science.add8943)
RBBP6 activates the pre-mRNA 3' end processing machinery in humans
– Genes and Development
(2022)
36,
210
(DOI: 10.1101/gad.349223.121)
Mechanism-based traps enable protease and hydrolase substrate discovery
– Nature
(2022)
602,
701
(DOI: 10.1038/s41586-022-04414-9)
Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons.
– Proceedings of the National Academy of Sciences of the United States of America
(2022)
119,
e2113845119
(DOI: 10.1073/pnas.2113845119)
Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites
– Mol Cell
(2021)
81,
4891
(DOI: 10.1016/j.molcel.2021.10.011)
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design.
– Nature Chemistry
(2021)
13,
1110
(DOI: 10.1038/s41557-021-00764-5)
Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase.
– Elife
(2021)
10,
e67075
(DOI: 10.7554/eLife.67075)
Sense codon reassignment enables viral resistance and encoded polymer synthesis.
– Science
(2021)
372,
1057
(DOI: 10.1126/science.abg3029)
Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS
– Nature Protocols
(2021)
16,
2345
(DOI: 10.1038/s41596-020-00464-3)
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