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Professor Jason Chin FMedSci

Portrait of jc482

Publications

Rapid and efficient generation of stable antibody-drug conjugates via an encoded cyclopropene and an inverse electron demand Diels-Alder reaction.
B Oller-Salvia, G Kym, JW Chin
– Angew Chem Int Ed Engl
(2018)
Toward an orthogonal central dogma
CC Liu, MC Jewett, JW Chin, CA Voigt
– Nature Chemical Biology
(2018)
14,
103
Labeling and identifying cell-specific proteomes in the mouse brain
TP Krogager, RJ Ernst, TS Elliott, L Calo, V Beránek, E Ciabatti, MG Spillantini, M Tripodi, MH Hastings, JW Chin
– Nature Biotechnology
(2017)
36,
156
Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells.
A Liaunardy-Jopeace, BL Murton, M Mahesh, JW Chin, JR James
– Nature structural & molecular biology
(2017)
24,
1155
Expanding and reprogramming the genetic code.
JW Chin
– Nature
(2017)
550,
53
Correction: Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling.
WD Lambert, SL Scinto, O Dmitrenko, SJ Boyd, R Magboo, RA Mehl, JW Chin, JM Fox, S Wallace
– Org Biomol Chem
(2017)
15,
7476
Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling
WD Lambert, SL Scinto, O Dmitrenko, SJ Boyd, R Magboo, RA Mehl, JW Chin, JM Fox, S Wallace
– Org Biomol Chem
(2017)
15,
6640
Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis
JA Gramespacher, AJ Stevens, DP Nguyen, JW Chin, TW Muir
– Journal of the American Chemical Society
(2017)
139,
8074
Biosynthesis and genetic encoding of phosphothreonine through parallel setection and deep sequencing
MS Zhang, SF Brunner, N Huguenin-Dezot, AD Liang, WH Schmied, DT Rogerson, JW Chin
– Nature methods
(2017)
14,
729
Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium( ii ) catalyst
TT-L Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring
– Chem. Sci.
(2017)
8,
3871
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Research Group

Research Interest Group

Email address

chin@mrc-lmb.cam.ac.uk