Professor of Chemistry & Chemical Biology
Publications
Automated orthogonal tRNA generation
– Nature chemical biology
(2024)
21,
657
(doi: 10.1038/s41589-024-01782-3)
Author Correction: Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS
– Nature Protocols
(2024)
1
(doi: 10.1038/s41596-024-01114-8)
Engineering Pyrrolysine Systems for Genetic Code Expansion and Reprogramming.
– Chemical reviews
(2024)
124,
11008
(doi: 10.1021/acs.chemrev.4c00243)
Capturing acyl-enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification.
– Nat Protoc
(2024)
19,
2967
(doi: 10.1038/s41596-024-01006-x)
Establishing a synthetic orthogonal replication system enables accelerated evolution in <i>E. coli</i>.
– Science (New York, N.Y.)
(2024)
383,
421
(doi: 10.1126/science.adk1281)
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism.
– Nature
(2024)
625,
603
(doi: 10.1038/s41586-023-06897-6)
Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly.
– Nature
(2023)
619,
555
(doi: 10.1038/s41586-023-06268-1)
Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs.
– Nature chemistry
(2023)
15,
948
(doi: 10.1038/s41557-023-01232-y)
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles.
– Nat Chem
(2022)
15,
61
(doi: 10.1038/s41557-022-01082-0)
Refactored genetic codes enable bidirectional genetic isolation.
– Science (New York, N.Y.)
(2022)
378,
516
(doi: 10.1126/science.add8943)
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