Professor of Chemistry & Chemical Biology
Publications
Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly
– Nature
(2023)
619,
555
(doi: 10.1038/s41586-023-06268-1)
Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs.
– Nature chemistry
(2023)
15,
948
(doi: 10.1038/s41557-023-01232-y)
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles.
– Nature chemistry
(2022)
15,
61
(doi: 10.1038/s41557-022-01082-0)
Refactored genetic codes enable bidirectional genetic isolation.
– Science (New York, N.Y.)
(2022)
378,
516
(doi: 10.1126/science.add8943)
RBBP6 activates the pre-mRNA 3′ end processing machinery in humans
– Genes Dev
(2022)
36,
210
(doi: 10.1101/gad.349223.121)
Mechanism-based traps enable protease and hydrolase substrate discovery
– Nature
(2022)
602,
701
(doi: 10.1038/s41586-022-04414-9)
Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons
– Proceedings of the National Academy of Sciences
(2022)
119,
e2113845119
(doi: 10.1073/pnas.2113845119)
Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites
– Mol Cell
(2021)
81,
4891
(doi: 10.1016/j.molcel.2021.10.011)
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design
– Nat Chem
(2021)
13,
1110
(doi: 10.1038/s41557-021-00764-5)
Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase.
– eLife
(2021)
10,
e67075
(doi: 10.7554/eLife.67075)
- 1 of 15