General dual functionalisation of biomacromolecules via a cysteine bridging strategy
SJ Walsh, J Iegre, H Seki, JD Bargh, HF Sore, JS Parker, JS Carroll, DR Spring
– Organic & Biomolecular Chemistry
(2020)
18,
Fsp3-rich and diverse fragments inspired by natural products as a collection to enhance fragment-based drug discovery.
AR Hanby, NS Troelsen, TJ Osberger, SL Kidd, KT Mortensen, DR Spring
– Chemical communications (Cambridge, England)
(2020)
56,
C(sp3)-H arylation to construct all-syn cyclobutane-based heterobicyclic systems: a novel fragment collection.
TJ Osberger, SL Kidd, TA King, DR Spring
– Chemical Communications
(2020)
56,
Diarylethene moiety as an enthalpy-entropy switch: Photoisomerizable stapled peptides for modulating p53/MDM2 interaction
AV Strizhak, O Babii, S Afonin, I Bakanovich, T Pantelejevs, W Xu, E Fowler, R Eapen, K Sharma, MO Platonov, VV Hurmach, L Itzhaki, M Hyvönen, AS Ulrich, DR Spring, IV Komarov
– Organic and Biomolecular Chemistry
(2020)
18,
Efficient and selective antibody modification with functionalised divinyltriazines.
AJ Counsell, SJ Walsh, NS Robertson, HF Sore, DR Spring
– Organic & biomolecular chemistry
(2020)
18,
Development of a Novel Cell-Permeable Protein–Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1
DJ Huggins, BS Hardwick, P Sharma, A Emery, L Laraia, F Zhang, AJ Narvaez, M Roberts-Thomson, AT Crooks, RG Boyle, R Boyce, DW Walker, N Mateu, GJ McKenzie, DR Spring, AR Venkitaraman
– ACS omega
(2019)
5,
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation.
A Venkitaraman
– Scientific Reports
(2019)
9,
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation.
P Sharma, R Mahen, M Rossmann, JE Stokes, B Hardwick, DJ Huggins, A Emery, DL Kunciw, M Hyvönen, DR Spring, GJ McKenzie, AR Venkitaraman
– Sci Rep
(2019)
9,
Direct Synthesis of N-Functionalized Dipropargylamine Linkers as Models for Use in Peptide Stapling
A Renzetti, RN Rutherford, K Fukumoto, D Kunciw, HF Sore, DR Spring
– Synlett
(2019)
30,
Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment-Based Drug Discovery.
TA King, HL Stewart, KT Mortensen, AJP North, HF Sore, DR Spring
– European Journal of Organic Chemistry
(2019)
2019,
