Professor David Spring

Professor of Chemistry & Chemical Biology

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Combinatorial Synthesis of Structurally Diverse Triazole-Bridged Flavonoid Dimers and Trimers

TH Sum, TJ Sum, WRJD Galloway, S Collins, DG Twigg, F Hollfelder, DR Spring

Molecules (Basel, Switzerland)

(2016)

E1230

(doi: 10.3390/molecules21091230)

Partially Saturated Bicyclic Heteroaromatics as an sp³-Enriched Fragment Collection

DG Twigg, N Kondo, SL Mitchell, WRJD Galloway, HF Sore, A Madin, DR Spring

Angew Chem Int Ed Engl

(2016)

12479

(doi: 10.1002/anie.201606496)

A Multidimensional Diversity‐Oriented Synthesis Strategy for Structurally Diverse and Complex Macrocycles

F Nie, DL Kunciw, D Wilcke, JE Stokes, WRJD Galloway, S Bartlett, HF Sore, DR Spring

Angew Chem Int Ed Engl

(2016)

11139

(doi: 10.1002/anie.201605460)

Synthesis of diverse semi-saturated bicyclic heteroaromatics

H Stewart, D Spring, T Moss

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2016)

252

Divergent synthesis of six biologically active 4-quinolone natural products isolated from Pseudonocardia sp CL38489

S Geddis, D Spring

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2016)

252

Partially saturated heteroaromatics as an sp3 enriched fragment collection

S Mitchell, D Twigg, N Kondo, D Spring

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2016)

252

Crystal Structure of CK2alpha with Compound 4 bound

P Brear, C De Fusco, KH Georgiou, D Spring, M Hyvonen

(2016)

(doi: 10.2210/pdb5csh/pdb)

Crystal Structure of CK2alpha with Compound 5 bound

P Brear, C De Fusco, KH Georgiou, D Spring, M Hyvonen

(2016)

(doi: 10.2210/pdb5csp/pdb)

Crystal Structure of CK2alpha with Compound 6 bound

P Brear, C De Fusco, KH Georgiou, D Spring, M Hyvonen

(2016)

(doi: 10.2210/pdb5csv/pdb)

Crystal Structure of CK2alpha

P Brear, C De Fusco, KH Georgiou, D Spring, M Hyvonen

(2016)

(doi: 10.2210/pdb5cvh/pdb)

Professor David Spring

Professor of Chemistry & Chemical Biology

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

Teaching

Publications

Publications

Research Group

Research Interest Groups

Telephone number

Email address

College

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge