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Yusuf Hamied Department of Chemistry

 

Professor of Supramolecular & Polymer Chemistry / Director of the Melville Laboratory for Polymer Synthesis

What we do

Our research interests include the synthesis of functional nanosystems, controlled polymer architectures and dynamic supramolecular assemblies through molecular recognition processes.

The underlying theme of our research lies at the interface between synthetic organic efforts on small molecules and macroscopic properties at the materials level, developing a macro-organic approach to chemistry. Dynamic supramolecular self-assembly of materials will be an area of great importance in the coming years, allowing for innovations in nanotechnology and at the biological and chemical interfaces.

We are particularly interested in exploring topics such as water-soluble and stimuli-responsive materials, template and imprinting technologies of functional polymers for use in chiral separations and enantioselective catalysis, and controlling material morphologies and architectures both in solution and in the solid state through rational design and a multi-step, hierarchical self-assembly process.

Watch Professor Scherman discuss his research

Take a tour of the Scherman Lab

Publications

Kinetic Locking of pH-Sensitive Complexes for Mechanically Responsive Polymer Networks
SJK O'Neill, YC Tse, Z Huang, X Chen, JA McCune, OA Scherman
– Journal of the American Chemical Society
(2025)
147,
33337
Explainable Deep Learning Framework for SERS Bioquantification
JK Zaki, J Tomasik, JA McCune, S Bahn, P Lió, OA Scherman
– ACS Sensors
(2025)
10,
6597
Meta-analysis of urinary metabolite GWAS studies identifies novel genome-wide significant loci.
JK Zaki, J Tomasik, JA McCune, OA Scherman, S Bahn
– Scientific reports
(2025)
15,
20375
Kinetically Arrested SERS-Active Aggregates for Biosensing.
NS Potter, K Sokołowski, RL Sala, JA McCune, OA Scherman
– Chemistry
(2025)
31,
e202500915
Supramolecular Conductive Hydrogels With Homogeneous Ionic and Electronic Transport
SJK O'Neill, M Ashizawa, AM McLean, RR-M Serrano, T Shimura, M Agetsuma, M Tsutsumi, T Nemoto, CDJ Parmenter, JA McCune, GG Malliaras, N Matsuhisa, OA Scherman
– Adv Mater
(2025)
37,
2415687
An All-in-One Nanoheater and Optical Thermometer Fabricated from Fractal Nanoparticle Assemblies.
WH Skinner, RL Sala, K Sokolowski, I Blein-Dezayes, NS Potter, S Mosca, B Gardner, JJ Baumberg, P Matousek, OA Scherman, N Stone
– ACS Nano
(2025)
19,
13779
Biomimetic Entropy-Dominant Molecular Hinges with Picomolar Affinity
Z Huang, AS Groombridge, G Wu, M Olesińska, X Chen, JA McCune, OA Scherman
– J Am Chem Soc
(2024)
146,
24244
Highly stretchable dynamic hydrogels for soft multilayer electronics
S O'Neill, Z Huang, X Chen, R Sala, J McCune, G Malliaras, O Scherman
– Sci Adv
(2024)
10,
eadn5142
Improved Imaging Surface for Quantitative Single-Molecule Microscopy
YP Zhang, E Lobanova, A Dworkin, M Furlepa, WS Yang, M Burke, JX Meng, N Potter, RL Sala, L Kahanawita, F Layburn, OA Scherman, CH Williams-Gray, D Klenerman
– ACS Applied Materials & Interfaces
(2024)
16,
37255
Single-Molecule Stoichiometry of Supramolecular Complexes
A McLean, RL Sala, BW Longbottom, AR Carr, JA McCune, SF Lee, OA Scherman
– Journal of the American Chemical Society
(2024)
146,
12877
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Research Groups

Research Interest Groups

Telephone number

01223 331797
34372 (shared)

Email address

oas23@cam.ac.uk