For the past few years, we have been developing structurally simple, easy-to-synthesize, modular, and tunable hydrazone-based functional materials.¹ This presentation will highlight our recent advances with these systems, with an emphasis on the use of hydrazones in the development of negative feedback loops,² reversible multicolor liquid crystal diplays (see below),³ and anion pumps.4
References:
1. B. Shao, I. Aprahamian Chem 2020, 6, 2161–2173.
2. D. Komáromy, A. N. Bismillah, V. A. Puranik, H. Fu, A. S. Y. Wong, I. Aprahamian, Chem 2026, 12, 102692.
3. I. Bala, J. T. Plank, B. Balamut, D. Henry, A. R. Lippert, I. Aprahamian, Nature Chem. 2024, 16, 2084–2090.
4. B. Shao, H. Fu, I. Aprahamian, Science 2024, 385, 544–549
BIO:
Professor Aprahamian received all his degrees (BSc in 1998, MS in 2000, and PhD in 2005) from the Hebrew University of Jerusalem, Israel. His doctoral research focused on NMR spectroscopic studies of alkali metal reduced polycyclic aromatic hydrocarbons. He then carried out postdoctoral research in (Nobel Laureate) Professor Sir Fraser Stoddart's group at UCLA, where he focused on the synthesis of switchable and highly ordered interlocked molecules in the form of bistable [n]rotaxanes. Dr. Aprahamian joined the faculty at Dartmouth College in August 2008, and was promoted to Associate Professor in 2014, and Full Professor in 2019. In 2025 he finished his three-year term as the Chair of his department. His research group focuses on using structurally simple, modular, and tunable hydrazone-based building blocks in the development of adaptive functional materials. Dr. Aprahamian is the recipient of several honors, including an NSF CAREER Award and the 2016 Cram-Lehn-Pedersen Prize in Supramolecular Chemistry. He is also a Fellow of the Royal Society of Chemistry and the Humboldt Foundation.
