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  • Currently displaying 23501 - 23520 of 30935 publications
Author(s)
Publication title
Journal Name
Publication year
Free energy of hydrolysis of tyrosyl adenylate and its binding to wild-type and engineered mutant tyrosyl-tRNA synthetases
TN Wells, CK Ho, AR Fersht
Biochemistry
(2002)
25
The valyl-tRNA synthetase from Bacillus stearothermophilus has considerable sequence homology with the isoleucyl-tRNA synthetase from Escherichia coli
TJ Borgford, NJ Brand, TE Gray, AR Fersht
Biochemistry
(2002)
26
Effects of engineering complementary charged residues into the hydrophobic subunit interface of tyrosyl-tRNA synthetase
WHJ Ward, DH Jones, AR Fersht
Biochemistry
(2002)
26
Site-directed mutagenesis in the effector site of Escherichia coli phosphofructokinase
FT Lau, AR Fersht, HW Hellinga, PR Evans
Biochemistry
(2002)
26
Synthesis of (+)-obafluorin, a .beta.-lactone antibiotic
C Lowe, Y Pu, JC Vederas
The Journal of Organic Chemistry
(2002)
57
Structure-activity relationships in engineered proteins: analysis of use of binding energy by linear free energy relationships.
AR Fersht, RJ Leatherbarrow, TN Wells
Biochemistry
(2002)
26
Structure-activity relationships in engineered proteins: characterization of disruptive deletions in the alpha-ammonium group binding site of tyrosyl-tRNA synthetase.
DM Lowe, G Winter, AR Fersht
Biochemistry
(2002)
26
STEREOCONTROLLED SYNTHESIS OF A C1-C15 SEGMENT FOR THE MARINE MACROLIDES SWINHOLIDE-A AND SCYTOPHYCIN-C - USE OF A VINYLOGOUS MUKAIYAMA ALDOL REACTION
I PATERSON, JD SMITH
The Journal of Organic Chemistry
(2002)
57
SYNTHESIS OF NOVEL SOLID-STATE COMPOUNDS IN SUPERCRITICAL SOLVENTS - PREPARATION AND STRUCTURE OF K2AG12SE7 IN SUPERCRITICAL ETHYLENEDIAMINE
PT Wood, WT Pennington, JW Kolis
Journal of the American Chemical Society
(2002)
114
Site-directed mutagenesis reveals transition-state stabilization as a general catalytic mechanism for aminoacyl-tRNA synthetases
TJ Borgford, TE Gray, NJ Brand, AR Fersht
Biochemistry
(2002)
26
Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis
AR Fersht
Biochemistry
(2002)
26
General equations for determining species involved in solution equilibria and equilibrium constants from solution molecular mass measurements
MG Davidson, R Snaith, D Stalke, DS Wright
The Journal of Organic Chemistry
(2002)
58
HIGH PI-FACE SELECTIVITY IN ANTI-ALDOL REACTIONS OF E-ENOL BORINATES FROM CHIRAL ALKOXYMETHYL KETONES - STEREOCONTROLLED SYNTHESIS OF A C24-C32 POLYOL SUBUNIT OF RAPAMYCIN
I PATERSON, RD TILLYER
The Journal of Organic Chemistry
(2002)
58
Investigation of transition-state stabilization by residues histidine-45 and threonine-40 in the tyrosyl-tRNA synthetase.
RJ Leatherbarrow, AR Fersht
Biochemistry
(2002)
26
Sequential 1H NMR assignments and secondary structure of hen egg white lysozyme in solution.
C Redfield, CM Dobson
Biochemistry
(2002)
27
Synthesis, Stability, and Antimicrobial Activity of (+)-Obafluorin and Related .beta.-Lactone Antibiotics
Y Pu, C Lowe, M Sailer, JC Vederas
The Journal of Organic Chemistry
(2002)
59
Relationships between apparent binding energies measured in site-directed mutagenesis experiments and energetics of binding and catalysis.
AR Fersht
Biochemistry
(2002)
27
Total Synthesis of (-)-Ebelactone A and B
I PATERSON, AN HULME
The Journal of Organic Chemistry
(2002)
60
Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism
AR Fersht, JW Knill-Jones, H Bedouelle, G Winter
Biochemistry
(2002)
27
Intramolecularly catalyzed sulfonamide hydrolysis. 8. Intramolecular nucleophilic catalysis by a neighboring hydroxyl group in acid-catalyzed benzenesulfonamide hydrolysis
A Wagenaar, AJ Kirby, JBFN Engberts
The Journal of Organic Chemistry
(2002)
49