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  • Currently displaying 22801 - 22820 of 30213 publications
Author(s)
Publication title
Journal Name
Publication year
Structure-activity relationships in engineered proteins: analysis of use of binding energy by linear free energy relationships
AR Fersht, RJ Leatherbarrow, TN Wells
Biochemistry
(2002)
26
Site-directed mutagenesis in the effector site of Escherichia coli phosphofructokinase.
FT Lau, AR Fersht, HW Hellinga, PR Evans
Biochemistry
(2002)
26
Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis.
AR Fersht
Biochemistry
(2002)
26
Effects of engineering complementary charged residues into the hydrophobic subunit interface of tyrosyl-tRNA synthetase
WHJ Ward, DH Jones, AR Fersht
Biochemistry
(2002)
26
The valyl-tRNA synthetase from Bacillus stearothermophilus has considerable sequence homology with the isoleucyl-tRNA synthetase from Escherichia coli.
TJ Borgford, NJ Brand, TE Gray, AR Fersht
Biochemistry
(2002)
26
Free energy of hydrolysis of tyrosyl adenylate and its binding to wild-type and engineered mutant tyrosyl-tRNA synthetases.
TN Wells, CK Ho, AR Fersht
Biochemistry
(2002)
25
Formaldehyde metabolism by Escherichia coli. Detection by in vivo 13C NMR spectroscopy of S-(hydroxymethyl)glutathione as a transient intracellular intermediate.
RP Mason, JK Sanders, A Crawford, BK Hunter
Biochemistry
(2002)
25
Internal thermodynamics of position 51 mutants and natural variants of tyrosyl-tRNA synthetase.
CK Ho, AR Fersht
Biochemistry
(2002)
25
Natural variation of tyrosyl-tRNA synthetase and comparison with engineered mutants.
MD Jones, DM Lowe, T Borgford, AR Fersht
Biochemistry
(2002)
25
INVESTIGATION OF TRANSITION-STATE STABILIZATION BY RESIDUES HISTIDINE-45 AND THREONINE-40 IN THE TYROSYL-TRANSFER RNA-SYNTHETASE
RJ Leatherbarrow, AR Fersht
Biochemistry
(2002)
26
SEQUENTIAL H-1-NMR ASSIGNMENTS AND SECONDARY STRUCTURE OF HEN EGG-WHITE LYSOZYME IN SOLUTION
C Redfield, CM Dobson
Biochemistry
(2002)
27
Relationships between apparent binding energies measured in site-directed mutagenesis experiments and energetics of binding and catalysis.
AR Fersht
Biochemistry
(2002)
27
Use of binding energy in catalysis analyzed by mutagenesis of the tyrosyl-tRNA synthetase
TN Wells, AR Fersht
Biochemistry
(2002)
25
Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism
AR Fersht, JW Knill-Jones, H Bedouelle, G Winter
Biochemistry
(2002)
27
Assignment of histidine resonances in the proton NMR (500 MHz) spectrum of subtilisin BPN' using site-directed mutagenesis
M Bycroft, AR Fersht
Biochemistry
(2002)
27
Characterization of a Partly Folded Protein by NMR Methods: Studies on the Molten Globule State of Guinea Pig α-Lactalbumin
J Baum, CM Dobson, PA Evans, C Hanley
Biochemistry
(2002)
28
Fine structure-activity analysis of mutations at position 51 of tyrosyl-tRNA synthetase.
AR Fersht, AJ Wilkinson, P Carter, G Winter
Biochemistry
(2002)
24
Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface.
DH Jones, AJ McMillan, AR Fersht, G Winter
Biochemistry
(2002)
24
A Magnetization-Transfer Nuclear Magnetic Resonance Study of the Folding of Staphylococcal Nuclease
PA Evans, RA Kautz, RO Fox, CM Dobson
Biochemistry
(2002)
28
INVIVO ENZYMOLOGY - A DEUTERIUM NMR-STUDY OF FORMALDEHYDE DISMUTASE IN PSEUDOMONAS-PUTIDA F61A AND STAPHYLOCOCCUS-AUREUS
RP Mason, JK Sanders
Biochemistry
(2002)
28