Yusuf Hamied Department of Chemistry

Publications by Professor Sir David Klenerman FMedSci FRS

Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
SW Chen, S Drakulic, E Deas, MM Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, GE De, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112.)
On-demand delivery of single DNA molecules using nanopipets.
AP Ivanov, P Actis, P Jönsson, D Klenerman, Y Korchev, JB Edel
ACS nano
(2015)
9
(doi: 10.1021/acsnano.5b00911)
Lipid peroxidation is essential for α-synuclein-induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
Journal of Neurochemistry
(2015)
133
(doi: 10.1111/jnc.13024)
SICM-Based Nanodelivery System for Local TRPV1 Stimulation
A López-Córdoba, P Jönsson, B Babakinejad, P Actis, P Novak, T Yasufumi, A Shevchuck, U Anand, P Anand, A Drews, A Ferrer-Montiel, D Klenerman, Y Korchev
Biophysical Journal
(2015)
108
(doi: 10.1016/j.bpj.2014.11.1808)
Single-molecule FRET reveals hidden complexity in a protein energy landscape
M Tsytlonok, SM Ibrahim, PJE Rowling, W Xu, MJ Ruedas-Rama, A Orte, D Klenerman, LS Itzhaki
Structure (London, England : 1993)
(2015)
23
(doi: 10.1016/j.str.2014.10.023)
Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging
M Palayret, H Armes, S Basu, AT Watson, A Herbert, D Lando, TJ Etheridge, U Endesfelder, M Heilemann, E Laue, AM Carr, D Klenerman, SF Lee
PLoS One
(2015)
10
(doi: 10.1371/journal.pone.0125438)
Single-Molecule Imaging Reveals that Small Amyloid-β1-42 Oligomers Interact with the Cellular Prion Protein (PrPC)
KA Ganzinger, P Narayan, SS Qamar, L Weimann, RT Ranasinghe, A Aguzzi, CM Dobson, J McColl, P St George-Hyslop, D Klenerman
Chembiochem : a European journal of chemical biology
(2014)
15
(doi: 10.1002/cbic.201402377)
Bayesian inference of accurate population sizes and FRET efficiencies from single diffusing biomolecules.
RR Murphy, G Danezis, MH Horrocks, SE Jackson, D Klenerman
Analytical chemistry
(2014)
86
(doi: 10.1021/ac501188r)
Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy.
TJ Etheridge, RL Boulineau, A Herbert, AT Watson, Y Daigaku, J Tucker, S George, P Jönsson, M Palayret, D Lando, E Laue, MA Osborne, D Klenerman, SF Lee, AM Carr
Nucleic Acids Res
(2014)
42
(doi: 10.1093/nar/gku726)
Corrigendum: Multifunctional Nanoprobes for Nanoscale Chemical Imaging and Localized Chemical Delivery at Surfaces and Interfaces
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV Macpherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201404979)
Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage
P Narayan, KM Holmström, D-H Kim, DJ Whitcomb, MR Wilson, P St George-Hyslop, NW Wood, CM Dobson, K Cho, AY Abramov, D Klenerman
Biochemistry
(2014)
53
(doi: 10.1021/bi401606f)
Contact-free scanning and imaging with the scanning ion conductance microscope
S Del Linz, E Willman, M Caldwell, D Klenerman, A Fernández, G Moss
Analytical Chemistry
(2014)
86
(doi: 10.1021/ac402748j)
A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging.
L Bell, A Seshia, D Lando, E Laue, M Palayret, SF Lee, D Klenerman
Sensors and Actuators B Chemical
(2014)
192
(doi: 10.1016/j.snb.2013.10.002)
Label-free measurements of the diffusivity of molecules in lipid membranes
B Johansson, F Höök, D Klenerman, P Jönsson
Chemphyschem
(2014)
15
(doi: 10.1002/cphc.201301136)
Imaging single nanoparticle interactions with human lung cells using fast ion conductance microscopy
P Novak, A Shevchuk, P Ruenraroengsak, M Miragoli, AJ Thorley, D Klenerman, MJ Lab, TD Tetley, J Gorelik, YE Korchev
Nano Lett
(2014)
14
(doi: 10.1021/nl404068p)
Single Molecule Fluorescence Studies of Protein Aggregates and their role in Neurodegenerative Disease
D Klenerman
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.067)
Nanopipet Based Nanoprobes for Single-Cell Analysis
YE Korchev, P Actis, S Tokar, P Novak, A Shevchuck, D Klenerman, EV Sviderskaya
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.4379)
Tau-Hsp70 Interaction at the Single-Molecule Level
F Kundel, M Kjaergaard, SL Shammas, SE Jackson, D Klenerman
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.406)
Single-Molecule Characterisation of Alpha-Synuclein Oligomers
MH Horrocks, SF Lee, S Gandhi, M Iljina, L Tosatto, CM Dobson, D Klenerman
BIOPHYSICAL JOURNAL
(2014)
106
Alpha-Synuclein Modulates [Ca2+]c of Neurons and Astrocytes that Trigger Cell Death
PR Stroh, MHR Ludtmann, NW Wood, D Klenerman, S Gandhi, AY Abramov
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.2951)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
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enquiries@ch.cam.ac.uk
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