Research Associate

Publications

Profiling Protein Aggregate Size Using Single-Molecule Array Technology.
D Böken, Y Wu, J Zhang, Z Xia, P Beltran-Lobo, CL Croft, S Weerasekera, A Heslegrave, H Zetterberg, A Keshavan, JM Schott, M Jimenez-Sanchez, DC Duffy, D Klenerman
Anal Chem
(2026)
98
A Correlative SICM-OPM Platform for Surface and Volumetric Imaging in Live Cells
W Hong, Z Zhang, A Li, T Sun, Y Wu, DM Vadukul, D Jones, B Li, F Liu, FA Aprile, Y Korchev, J Gorelik, D Klenerman, A Shevchuk
Adv Sci (Weinh)
(2026)
13
USP2 promotes metabolic dysfunction-associated steatotic liver disease progression via stabilization of PPARγ
H Luo, C Zhu, Y Wang, Y Dai, P Hao, H Cai, W Bai, Z Zhang, J Wan, Y Zhang, Y Sun, Z Zhang, Y Wu, Y Zhai, W Wu, H Lei, H Xu, M He, Y Wu
Cell Death and Differentiation
(2025)
33
Targeting USP2 induces degradation of PML-RARα with or without drug-resistant mutations in acute promyelocytic leukemia
J Zhang, W Wu, Y Wang, Y Zhang, Y Wang, W Bai, Z Zhang, C Zhu, Y Wu, Z Zhang, L Yang, H Lei, H Xu, L Zhou, Y Wu
Acta Biochim Biophys Sin (Shanghai)
(2025)
58
SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
S Kedia, E Fertan, Y Wu, YP Zhang, G Meisl, JYL Lam, F K Wiseman, WA McEwan, A Quaegebeur, MG Spillantini, JSH Danial, D Klenerman
Cell chemical biology
(2025)
32
Detecting the Undetectable: Advances in Methods for Identifying Small Tau Aggregates in Neurodegenerative Diseases
D Böken, Y Wu, Z Zhang, D Klenerman
ChemBioChem
(2025)
26
Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform
D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman
Anal Chem
(2024)
97
Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab
D Klenerman, E Fertan, J Lam, G Albertini, M Dewilde, Y Wu, O Akingbade, D Böken, E English, B De Strooper
(2024)
Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab
E Fertan, JYL Lam, G Albertini, M Dewilde, Y Wu, OES Akingbade, D Böken, EA English, B De Strooper, D Klenerman
(2024)
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
Y Wang, Y Zhang, H Luo, W Wei, W Liu, W Wang, Y Wu, C Peng, Y Ji, J Zhang, C Zhu, W Bai, L Xia, H Lei, H Xu, L Yin, W Weng, L Yang, L Liu, A Zhou, Y Wei, Q Zhu, W Zhu, Y Yang, Z Xu, Y Wu
Acta Pharm Sin B
(2024)
14

Research Group

Email address