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Yusuf Hamied Department of Chemistry

 

Tom Wharton

Research Associate

Publications

A Platform for SpyCatcher Conjugation to Native Antibodies
S Krajcovicova, T Wharton, CL Driscoll, TA King, MR Howarth, DR Spring
– Chemical Science
(2025)
(doi: 10.1039/d5sc02286j)
Methods for the Generation of Single-Payload Antibody-Drug Conjugates
T Wharton, DR Spring
– ChemMedChem
(2025)
20,
e202500132
(doi: 10.1002/cmdc.202500132)
Advances in the Release of Amide-Containing Molecules
T Wharton, DR Spring
– Chemistry – A European Journal
(2025)
31,
e202404413
(doi: 10.1002/chem.202404413)
Single-Payload Bioconjugation to Native Antibodies And A General Method for the Self-Immolative Release of Amide-Containing Molecules
T Wharton
(2024)
(doi: 10.17863/CAM.114785)
Ideas Behind the Tryptophan-Mediated Petasis Reaction (TMPR) Concept for Peptide Stapling
S Krajcovicova
– ChemMedChem
(2024)
19,
e202400148
(doi: 10.1002/cmdc.202400148)
Unlocking Amides: A General Method for the Self‐Immolative Release of Amide‐Containing Molecules
T Wharton, F Crawshay‐Williams, T Schober, RA Floto, DR Spring
– Angewandte Chemie
(2024)
136,
e202402267
(doi: 10.1002/ange.202402267)
Unlocking Amides: A General Method for the Self-Immolative Release of Amide-Containing Molecules
T Wharton, F Crawshay-Williams, T Schober, RA Floto, DR Spring
– Angew Chem Int Ed Engl
(2024)
63,
e202402267
(doi: 10.1002/anie.202402267)
Disulfide re-bridging reagents for single-payload antibody-drug conjugates.
TA King, SJ Walsh, M Kapun, T Wharton, S Krajcovicova, MS Glossop, DR Spring
– Chem Commun (Camb)
(2023)
59,
9868
(doi: 10.1039/d3cc02980h)

Research Group

Telephone number

01223 336361 (shared)

Email address

tw529@cam.ac.uk

College

Trinity College

    Study at Cambridge

    About the University

    Research at Cambridge