Research Associate

Dr Saan Voss is a UKRI Knowledge Transfer Partner between the University of Cambridge (Department of Chemistry) and Bicycle Therapeutics.

Saan received his undergraduate training in pharmaceutical science at the Freie Universität Berlin, before relocating to the Australian National University as fully funded PhD candidate. He earned his PhD in Chemistry for his pioneering work on a novel class of constrained peptides - called 'Bismuth Bicycles' - Angewandte Chemie 2022 & 2024 (media coverage by C&EN magazine 2022). Saan then joined a cross-sector collaboration between the University of Cambridge and Bicycle Therapeutics as UKRI Knowledge Transfer Partner after having secured his first research grant (valued at £330k) before finishing up his PhD program. Today, Saan is driving  the development of next-generation therapeutics by applying his broad expertise ranging from medicinal chemistry over chemical biology to cell biology. He is part of an interdisciplinary research team that works across academia and industry aiming to develop creative solutions to global health challenges. Saan is interested in developing concept designs by reimagining molecular architectures to develop the therapeutics of the future and has a growing interest in synthetic biology.

Saan has secured over £500k in funding so far and has been recognised with a number of prizes from international societies including the Royal Australian Chemical Institute and the Italian Peptide Society (1st Luis Moroder Award).

Publications

Bismuth Bicycles
S Voss, A Sagar, A Tiberghien, RJL Hughes, L Chen, I Rioja, M Frigerio, MJ Skynner, DR Spring
Journal of Peptide Science
(2026)
32
Characterisation of ten NS2B-NS3 proteases: Paving the way for pan-flavivirus drugs
S Voss, J Rademann, C Nitsche
Antiviral Research
(2024)
226
Cell‐Penetrating Peptide‐Bismuth Bicycles**
S Voss, LD Adair, K Achazi, H Kim, S Bergemann, R Bartenschlager, EJ New, J Rademann, C Nitsche
Angewandte Chemie
(2024)
136
Cell-Penetrating Peptide-Bismuth Bicycles.
S Voss, LD Adair, K Achazi, H Kim, S Bergemann, R Bartenschlager, EJ New, J Rademann, C Nitsche
Angewandte Chemie (International ed. in English)
(2024)
63
Exploring biocompatible chemistry to create stapled and photoswitchable variants of the antimicrobial peptide aurein 1.2
AE Coram, R Morewood, S Voss, JL Price, C Nitsche
Journal of peptide science : an official publication of the European Peptide Society
(2023)
30
Peptide–Bismuth Bicycles: In Situ Access to Stable Constrained Peptides with Superior Bioactivity
S Voss, J Rademann, C Nitsche
Angewandte Chemie
(2021)
134
Peptide-Bismuth Bicycles: In Situ Access to Stable Constrained Peptides with Superior Bioactivity
S Voss, J Rademann, C Nitsche
Angewandte Chemie International Edition
(2021)
61
Targeting the protease of West Nile virus
S Voss, C Nitsche
RSC medicinal chemistry
(2021)
12
Inhibitors of the Zika virus protease NS2B-NS3
S Voss, C Nitsche
Bioorganic & medicinal chemistry letters
(2020)
30

Research Group

Email address