jiapeng Wei

Research Associate

Publications

Potent substoichiometric inhibition of alpha-synuclein aggregation by de novo oligomer-binding proteins

Y Zhang, HL Han, L Ortigosa-Pascual, UZ Miles, J Wei, L Berkowicz, F Snow, D Tu, G Meisl, S Sansaria, TJ Nott, H Laman, R Halfmann, AC McShan, DD Sahtoe, TPJ Knowles

(2026)

(doi: 10.64898/2026.07.13.738012)

Reversible peptide self-assembly enables sustained drug delivery with tuneable pharmacokinetics

TW Herling, J Wei, S Genapathy, C Rivera, M Persson, P Gennemark, D Workman, D Lundberg, E Bernard, H Bolt, MY Arteta, S Will, A Bak, D Hornigold, TPJ Knowles, ALG dos Santos

(2026)

(doi: 10.64898/2026.03.25.714189)

Oligomers mediate the spatial transmission of Aβ peptide aggregation

Q Peter, C Taylor, U Lapinska, J Wei, TCT Michaels, P Arosio, S Linse, TPJ Knowles

Communications Chemistry

(2026)

(doi: 10.1038/s42004-025-01837-z)

Secondary nucleation of α-Synuclein drives Mitochondria dysfunctions and Lewy body formation in Parkinson’s Disease

S De, E Prescott, J Wei, E Garland, A Urbanek, F Capriglia, W Molenkamp, D Rhodes, L Heywood, A Schwartzentruber, E Stephen, R Hughes, O Bandmann, M Collins, S Linse, A Abelein, J Johansson, M Vendruscolo, J Highley, T Knowles, H Mortiboys

(2025)

(doi: 10.21203/rs.3.rs-7657706/v1)

Secondary nucleation of α-Synuclein drives Mitochondria dysfunctions and Lewy body formation in Parkinson’s Disease

EE Prescott, J Wei, EF Garland, A Urbanek, F Capriglia, WH Molenkamp, DP Rhodes, L Heywood, A Schwartzentruber, E Stephen, R Hughes, O Bandmann, MO Collins, S Linse, A Abelein, J Johansson, M Vendruscolo, JR Highly, TPJ Knowles, H Mortiboys, S De

(2025)

(doi: 10.1101/2025.09.17.676873)