Professor Jason Chin FMedSci FRS

Professor of Chemistry & Chemical Biology

Publications

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase.

S Virdee, Y Ye, DP Nguyen, D Komander, JW Chin

Nature Chemical Biology

(2010)

750

(doi: 10.1038/nchembio.426)

Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization

M Lammers, H Neumann, JW Chin, LC James

Nature chemical biology

(2010)

331

(doi: 10.1038/nchembio.342)

Genetically Encoded Photocontrol of Protein Localization in Mammalian Cells

A Gautier, DP Nguyen, H Lusic, W An, A Deiters, JW Chin

Journal of the American Chemical Society

(2010)

132

4086

(doi: 10.1021/ja910688s)

Evolved orthogonal ribosome purification for in vitro characterization

OPT Barrett, JW Chin

Nucleic Acids Res

(2010)

2682

(doi: 10.1093/nar/gkq120)

Regulation of cellular metabolism by protein lysine acetylation.

S Zhao, W Xu, W Jiang, W Yu, Y Lin, T Zhang, J Yao, L Zhou, Y Zeng, H Li, Y Li, J Shi, W An, SM Hancock, F He, L Qin, J Chin, P Yang, X Chen, Q Lei, Y Xiong, K-L Guan

Science

(2010)

327

1000

(doi: 10.1126/science.1179689)

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

H Neumann, K Wang, L Davis, M Garcia-Alai, JW Chin

Nature

(2010)

464

441

(doi: 10.1038/nature08817)

De Novo Generation of Mutually Orthogonal Aminoacyl-tRNA Synthetase/tRNA Pairs

H Neumann, AL Slusarczyk, JW Chin

Journal of the American Chemical Society

(2010)

132

2142

(doi: 10.1021/ja9068722)

Regulation of Nucleosome Conformational Dynamics by Post-Translational Histone Modifications Studied with Single-Pair FRET

R Buning, W Koopmans, H Neumann, J Chin, J van Noort

Biophysical Journal

(2010)

475a

(doi: 10.1016/j.bpj.2009.12.2590)

A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation

H Neumann, SM Hancock, R Buning, A Routh, L Chapman, J Somers, T Owen-Hughes, J van Noort, D Rhodes, JW Chin

Molecular Cell

(2009)

153

(doi: 10.1016/j.molcel.2009.07.027)

Genetically Encoding N-epsilon-Methyl-L-lysine in Recombinant Histones

DP Nguyen, MM Garcia Alai, PB Kapadnis, H Neumann, JW Chin

Journal of the American Chemical Society

(2009)

131

14194

(doi: 10.1021/ja906603s)

Professor Jason Chin FMedSci FRS

Professor of Chemistry & Chemical Biology

Publications

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About the Department

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Study at Cambridge

About the University

Research at Cambridge