Epidemiological insights from a large-scale investigation of intestinal helminths in Medieval Europe.
PG Flammer, H Ryan, SG Preston, S Warren, R Přichystalová, R Weiss, V Palmowski, S Boschert, K Fellgiebel, I Jasch-Boley, M-S Kairies, E Rümmele, D Rieger, B Schmid, B Reeves, R Nicholson, L Loe, C Guy, T Waldron, J Macháček, J Wahl, M Pollard, G Larson, AL Smith
– PLoS Negl Trop Dis
(2020)
14,
Adventures in drugging undruggable targets
DR Spring
– JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
(2020)
63,
Divergent Synthesis of Novel Cylindrocyclophanes that Inhibit Methicillin‐Resistant Staphylococcus aureus (MRSA)
JJ Freudenreich, S Bartlett, NS Robertson, SL Kidd, S Forrest, HF Sore, WRJD Galloway, M Welch, DR Spring
– ChemMedChem
(2020)
15,
Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells
DA Russell, HR Bridges, R Serreli, SL Kidd, N Mateu, TJ Osberger, HF Sore, J Hirst, DR Spring
– Journal of natural products
(2020)
83,
Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
SL Kidd, E Fowler, T Reinhardt, T Compton, N Mateu, H Newman, D Bellini, R Talon, J McLoughlin, T Krojer, A Aimon, A Bradley, M Fairhead, P Brear, L Díaz-Sáez, K McAuley, HF Sore, A Madin, DH O'Donovan, KVM Huber, M Hyvönen, F von Delft, CG Dowson, DR Spring
– Chemical Science
(2020)
11,
2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa.
AC McVey, S Bartlett, M Kajbaf, A Pellacani, V Gatta, P Tammela, DR Spring, M Welch
– International Journal of Molecular Biosciences (IJMS)
(2020)
21,
Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design
PR Curran, CJ Radoux, MD Smilova, RA Sykes, AP Higueruelo, AR Bradley, BD Marsden, DR Spring, TL Blundell, AR Leach, WR Pitt, JC Cole
– J Chem Inf Model
(2020)
60,
Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents
TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, JS Parker, DR Spring, I Paterson
– Chemical Communications
(2020)
56,
Sulfatase-cleavable linkers for antibody-drug conjugates.
JD Bargh, SJ Walsh, A Isidro-Llobet, S Omarjee, JS Carroll, DR Spring
– Chemical Science
(2020)
11,
Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction
K Sharma, AV Strizhak, E Fowler, W Xu, B Chappell, HF Sore, WRJD Galloway, MN Grayson, YH Lau, LS Itzhaki, DR Spring
– ACS omega
(2020)
5,
